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Project
Outside in or inside out? Exploring the evolutionary origin of vertebrate teeth
We propose that vertebrate teeth evolutionarily arose where outpocketings of the endoderm-lined pharynx (pouches), contacted the ectoderm-lined skin to form gill slits. Using zebrafish, we will test the correlation between tooth and gill slit formation, reveal the extent of ectoderm and endoderm in pouches and gill slits, and test the requirement for endoderm and ectoderm in tooth formation.
Date:1 Sep 2015 → 30 Sep 2022
Keywords:pharyngeal pouches, zebrafish, teeth, ectoderm, endoderm, odontodes, gill slits
Disciplines:Veterinary medicine, Dentistry, Animal biology, Genetics