Pain and autonomic dysfunction in the hypermobility type of Ehlers-Danlos Syndrome

The aim of this research proposal is to assess the nature of pain, using a validated questionnaire (PainDetect) and physiological testing (Quantitative Sensory Testing), to assess autonomic function by means of a validated non-invasive test battery (Autonomic Reflex Screen) and finally to investigate an association between dysautonomia and pain in female patients with EDS-HT and matched healthy controls.