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Hemadsorption: A New Therapeutic Option for Selected Cases of Bromazepam Intoxication

Journal Contribution - Journal Article

Benzodiazepine ingestion is frequent in patients admitted to ICU for intoxications. Generally, a supportive approach by securing the airway, breathing, and circulation is sufficient. Flumazenil is a well-known antidote for benzodiazepines but does not influence its elimination. Following preclinical data, we applied for the first time in humans a hemadsorption filter in a patient with a bromazepam intoxication. This technique proved to be effective in eliminating bromazepam in a patient with CHILD-C cirrhosis. We conclude that hemadsorption is a viable option to reduce length of ICU stay or intubation in slow metabolizers without contraindications.
Journal: Case Reports in Nephrology and Dialysis
ISSN: 2296-9705
Issue: 3
Volume: 12
Pages: 163-166
Publication year:2022
Accessibility:Open