Organisation
Renzo Mancuso Lab
Research Group
Current researchers
1 - 10 of 17 results
- Renzo Mancuso (Responsible)
- Baukje Bijnens (Member)
- Rita Cacace (Member)
- Nicola Fattorelli (Member)
- Laura Fumagalli (Member)
- Joana Garcia Garcia (Member)
- Lena Jutz (Member)
- Cindy Keller (Member)
- Teun Klein Gunnewiek (Member)
- Miranda Lastra Osua (Member)
Projects
1 - 10 of 12
- Marie Curie voor Alma MohebianyFrom1 Sep 2024 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- SAO-FRMA - Standard grantFrom1 Jan 2024 → TodayFunding: Private funding of national origin - undefined
- Impact of ABCA7 mutations on the microglial endolysosomal functionFrom1 Jan 2024 → TodayFunding: Other international institutions, not mentioned elsewhere
- APOE modifiers of human microglia function in Alzheimer's diseaseFrom1 Jan 2023 → TodayFunding: Other international institutions, not mentioned elsewhere
- Deciphering the microglia-neuron interactions in human Alzheimer's diseaseFrom1 Jan 2023 → TodayFunding: HORIZON.1.1 - European Research Council (ERC)
- Microglia-synapse molecular interactions in neurodegenerative disorders (Marie curie individual fellowship Teun Klein Gunnewiek )From1 May 2022 → TodayFunding: Other EU initiatives out of framework
- VIB Grant for Renzo Mancuso Lab_Period:2022-01-01-2026-12-31From1 Jan 2022 → TodayFunding: FRI - Project driven research
- From gene to function: Unraveling the molecular mechanisms of Alzheimer-associated ABCA7 risk variants in microglia biologyFrom1 Jan 2022 → TodayFunding: Private funding of national origin - undefined
- From genetics to the cellular phase of Alzheimer’s disease: untangling the role of lipid pathways in microglia responses to amyloid pathologyFrom1 Jul 2021 → 30 Jun 2023Funding: Foreign foundations, funds with scientific view
- DAVID HAGUE EARLY CAREER INVESTIGATOR OF THE YEAR AWARD: ARUK-YI2020-003From1 Jan 2021 → 31 Dec 2021Funding: Other international institutions, not mentioned elsewhere
Publications
1 - 8 of 8
- Stem-cell-derived human microglia transplanted into mouse brain to study human disease.(2021)
Authors: Nicola Fattorelli, Anna Martinez Muriana, Ivana Geric, Bart De Strooper, Renzo Mancuso
Pages: 1013–1033 - Microglia states and nomenclature: A field at its crossroads.(2022)
Authors: Bart De Strooper, Renzo Mancuso
Pages: 3458-3483 - Xenografted human microglia display diverse transcriptomic states in response to Alzheimer's disease-related amyloid-ß pathology.(2024)
Authors: Renzo Mancuso, Nicola Fattorelli, Anna Martinez Muriana, Emma Davis, Ivana Geric, Jessie Premereur, Paula Polanco Miquel, Baukje Bijnens, Pranav Preman, Lutgarde Serneels, et al.
Pages: e-pub - S100A8-enriched microglia populate the brain of tau-seeded and accelerated aging mice.(2024)
Authors: Baukje Bijnens
Pages: e-pub - Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease.(2023)
Authors: Renzo Mancuso
Pages: 92 - microRNA-132 regulates gene expression programs involved in microglial homeostasis.(2023)
Authors: Hannah Walgrave, Emma Davis, Susanne Rianneke Sierksma, Nicola Thrupp, Renzo Mancuso, Mark Fiers, Bart De Strooper, Evgenia Salta
Pages: 106829 - The y-secretase substrate proteome and its role in cell signaling regulation.(2023)
Authors: Pengfei Hou, Magdalena Zielonka, Lutgarde Serneels, Anna Martinez Muriana, Nicola Fattorelli, Dries T'Syen, Sriram Balusu, Mark Fiers, Renzo Mancuso, Bart De Strooper
Pages: 4106-4122.e10 - A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons.(2023)
Authors: Jimmy Beckers, Arun Kumar Tharkeshwar Raghunath, Laura Fumagalli, Matilde Contardo, Evelien Van Schoor, Raheem Fazal, Renzo Mancuso, Ludo Van Den Bosch, Philip Van Damme
Pages: 151