Organisation
Cools Lab
Research Group
Current researchers
1 - 10 of 15 results
- Cools J (Responsible)
- Margo Aertgeerts (Member)
- Veloso Alexandra (Member)
- Sofie Demeyer (Member)
- Lukas Lauwereins (Member)
- Sarah Meyers (Member)
- Ana-Lucia Rocha Iraizos (Member)
- Yilke Schoenmaekers (Member)
- Thomas Slegers (Member)
- Flore Sneyers (Member)
Projects
1 - 5 of 5
- VIB Grant for Cools Lab_Period:2022-01-01-2026-12-31From1 Jan 2022 → TodayFunding: FRI - Project driven research
- HEALTHCARE ALLIANCE FOR RESOURCEFUL MEDICINES OFFENSIVE AGAINST NEOPLASMS IN HEMATOLOGY – PLUS’ —‘HARMONY PLUS’From1 Oct 2020 → 30 Sep 2023Funding: Other EU initiatives out of framework
- Single-cell map of the composition and evolution of T-cell acute lymphoblastic leukemiaFrom1 Apr 2019 → 31 Mar 2021Funding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- Health alliance for resourceful medicines offensive against neoplasms in hematologyFrom1 Jan 2017 → 31 Dec 2021Funding: Other EU initiatives out of framework
- VIB Grant for Cools Lab_Period:2017-01-01-2021-12-31From1 Jan 2017 → 31 Dec 2021Funding: FRI - Project driven research
Publications
1 - 10 of 60
- PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia.(2021)
Authors: Inge Govaerts, Cristina Prieto Fernández, Charlien Vandersmissen, Jan Cools
Pages: 97 - Combination therapy of a PSEN1-selective ?-secretase inhibitor with dexamethasone and an XPO1 inhibitor to target T-cell acute lymphoblastic leukemia.(2023)
Authors: Charlien Vandersmissen, Cristina Prieto Fernández, Jan Cools
Pages: 2507-2512 - The Fifth Year of HemaSphere.(2021)
Authors: Jan Cools
Pages: e588 - T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development(2019)
Authors: Charles De Bock, Mark Fiers, Jan Cools
Pages: e204-e207 - The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic Leukemia(2017)
Authors: Jolien De Bie, Jan Cools
Pages: 2528-2541 - Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires ß-catenin activity to drive T-cell acute lymphoblastic leukemia.(2021)
Authors: Quentin Van Thillo, Jolien De Bie, Sofie Demeyer, Jan Cools, Charles De Bock
Pages: 4164 - Ruxolitinib Synergizes With Dexamethasone for the Treatment of T-cell Acute Lymphoblastic Leukemia.(2019)
Authors: Delphine Verbeke, Jan Cools
Pages: e310 - PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.(2022)
Authors: Matteo Rossi, Patricia Altea Manzano, Margherita Demicco, Ginevra Doglioni, Anke Vandekeere, Alejandro Cuadros, Juan Fernandez Garcia, Carla Riera Domingo, Hamza Furkan Alkan, Lindsay Broadfield, et al.
Pages: 747-753 - Overexpression of wild type IL-7Ra promotes T-cell acute lymphoblastic leukemia/lymphoma.(2021)
Authors: Sofie Demeyer, Jan Cools
Pages: 1040-1052 - The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia.(2020)
Authors: Delphine Verbeke, Sofie Demeyer, Cristina Prieto Fernández, Charles De Bock, Jolien De Bie, Jan Cools
Pages: 5747-5758