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Researcher
Diether Lambrechts
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Morphological sciences, Oncology
- See also: Diether Lambrechts (KU Leuven)
Affiliations
- Laboratory of Translational Genetics (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2017 → Today - VIB-KU Leuven Center for Cancer Biology (Research Center)
Responsible
From1 Jan 2017 → Today - Lambrechts Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory of Translational Genetics (VIB-KU Leuven) (Division)
Member
From1 Jan 2012 → Today - Centre for Molecular and Vascular Biology (Division)
Member
From1 Oct 2003 → 30 Sep 2005 - Department of Cellular and Molecular Medicine (Department)
Member
From1 Oct 1999 → 30 Sep 2003
Projects
1 - 7 of 7
- EXPANDing Immune Cells and their Tumor Antigens during checkpoint immunotherapyFrom1 Jan 2023 → TodayFunding: HORIZON.1.1 - European Research Council (ERC)
- VIB Grant for Lambrechts Lab_Period:2022-01-01-2026-12-31From1 Jan 2022 → TodayFunding: FRI - Project driven research
- CIRCULATING TUMOR DNA AS AN EPIGENETIC BIOMARKER FOR TUMOR RESPONSE’ — ‘INITIATOR’ - ERC POCFrom1 Aug 2020 → 31 Jan 2022Funding: HORIZON.1.1 - European Research Council (ERC)
- RESISTANCE UNDER COMBINATORIAL TREATMENT IN ER+ AND ER- BREAST CANCER.’ — ‘RESCUER’From1 Jan 2020 → TodayFunding: Other EU initiatives out of framework
- 'Advancing a Precision Medicine Paradigm in metastatic Colorectal Cancer: Systems based patient stratification solutions’ — ‘COLOSSUS’From1 Jan 2018 → 31 Dec 2022Funding: Other EU initiatives out of framework
- Exploiting GLIOblastoma intractability to address European research TRAINing needs in translational brain tumour research, cancer systems medicine and integrative multi-omics (GLIOTRAIN) - Marie Sklodowska-Curie actions (ITN)From1 Sep 2017 → 31 Aug 2021Funding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- VIB Grant for Lambrechts Lab_Period:2017-01-01-2021-12-31From1 Jan 2017 → 31 Dec 2021Funding: FRI - Project driven research
Publications
1 - 10 of 230
- Comparison of the single-cell and single-nucleus hepatic myeloid landscape within decompensated cirrhosis patients.(2024)
Authors: Dora Bihary, Bram Boeckx, Diether Lambrechts
Pages: 1346520 - Heterozygous mutations in the C-terminal domain of COPA underlie a complex autoinflammatory syndrome.(2024)
Authors: Bram Boeckx, Sebastian Munck, Diether Lambrechts
Pages: e-pub - A phase II, multicenter, open-label study of abemaciclib and letrozole in patients with estrogen receptor-positive rare ovarian cancer: ALEPRO trial.(2024)
Authors: Diether Lambrechts
Pages: 627-630 - Immune checkpoint biology in health & disease: Immune checkpoint biology and autoimmunity in cancer patients.(2024)
Authors: Pierre Van Mol, Elena Donders, Diether Lambrechts
Pages: 181-206 - CD4+ T cell activation distinguishes response to antiPD-L1+anti-CTLA4 therapy from anti-PD-L1 monotherapy(2024)
Authors: Amelie Franken, Aurelie Mechels, Orian Bricard, Jieyi Xiong, Bram Boeckx, Diether Lambrechts
Pages: 541-558.e7 - Transcriptomic characterization of the histopathological growth patterns in breast cancer liver metastases.(2024)
Authors: Bram Boeckx, Diether Lambrechts
Pages: e-pub - A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma.(2024)
Authors: Joanna Pozniak, Dennis Pedri, Ewout Landeloos, Ada Nowosad, Niccolo Roda, Carlos Ariel Pulido Vicuna, Lotte Pollaris, Ruth Seurinck, Benjamin Rombaut, Frank Vernaillen, et al.
Pages: 166-183.e25 - Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer.(2024)
Authors: Diether Lambrechts, Jieyi Xiong
Pages: 105003 - Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders.(2024)
Authors: Diether Lambrechts
Pages: e-pub - Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study.(2024)
Authors: Sam Vanmassenhove, Bram Boeckx, Pierre Van Mol, Diether Lambrechts
Pages: e247-e260
Patents
1 - 10 of 10
- DISEASE DETECTION IN LIQUID BIOPSIES (Inventor)
- BIOMARKERS PREDICTING RESPONSE OF BREAST CANCER TO IMMUNOTHERAPY (Inventor)
- DISEASE DETECTION IN LIQUID BIOPSIES (Inventor)
- PREDICTING CHRONIC ALLOGRAFT INJURY THROUGH AGE-RELATED DNA METHYLATION (Inventor)
- PREDICTING CHRONIC ALLOGRAFT INJURY THROUGH AGE-RELATED DNA METHYLATION (Inventor)
- RETROTRANSPOSON BIOMARKERS (Inventor)
- RETROTRANSPOSON BIOMARKERS (Inventor)
- DISEASE DETECTION IN LIQUID BIOPSIES (Inventor)
- DETECTION OF OVARIAN CANCER IN LIQUID BIOPSIES (Inventor)
- PREDICTING CHRONIC ALLOGRAFT INJURY THROUGH AGE-RELATED DNA METHYLATION (Inventor)