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Cognitive Genetics (COGNET)
Main organisation:Department of Biomedical Sciences
Lifecycle:1 Oct 2003 → Today
Organisation profile:The mission of the research group "cognitive genetics" is to identify genetic causes of cognitive disorders and to study the defective genes in order to eventually develop rational therapy. We identify novel causes of cognitive disorders starting from affected families or from patients with specific chromosomal abnormalities, including microdeletions, translocations and fragile sites. To achieve this, we have developed novel technologies and optimized existing methods. For the functional study of the genes of interest, we rely heavily on mouse models. These are fully characterized and are also used in drug trials. To this end, our studies on fragile X syndrome, a common form of mental retardation, have initiated clinical trials in patients.
Keywords:CYTOGENETICS, COGNITIVE PROCESSES, FRAGILE X-SYNDROME, MENTAL RETARDATION, MEDICAL GENETICS, AUTISM, INTELLECTUAL DISABILITY, MOUSE MODELS
Disciplines:Biochemistry and metabolism, Genetics, Systems biology, Medical biochemistry and metabolism, Molecular and cell biology