Organisation
Embriology and Human Genetics
Research Group
Topic A : assisted fertilization for severe male-factor infertility Infertile couples who cannot be treated by standard in vitro fertilization, a.single spermatozoon is injected by micro-manipulation technique into the oocyte. Factors influencing the success of intracytoplasmatic sperm injection. Topic B : Cryopreservation of oocytes and embryos Since the number of oocytes and embryos which are replaced has to be limited to two or three, supernumerary oocytes and embryos can be cryopreserved. Assessment of different cryopreservation procedures for human oocytes and embryos Topic C : Preimplantation diagnosis Prenatal diagnosis can be done on one or two blastomeres of eight-cell embryos, only embryos which are non-affected will be replaced in couples at risk for genetic diseases. Preimplantation diagnosis on single cells for: Tay Sachs disease Gender determination Cystic fibrosis