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Organisation
Experimental Cardiology
Division
Main organisation:Department of Cardiovascular Sciences
Lifecycle:1 Oct 2005 → Today
Organisation profile:
Research focuses on molecular mechanisms of excitation-contraction coupling in cardiac myocytes (electrophysiology, advanced calcium imaging), cellular remodeling in cardiac disease: ischemia and heart failure, mechanisms of arrhythmias. Research further aims to understand epigenetic mechanisms of adaptive and maladaptive remodeling of cardiac myocytes. Other work focuses on molecular pathways in metabolic cardiovascular diseases and biomarkers.
Keywords:Cardiology
Disciplines:Cardiac and vascular medicine
Current researchers
1 - 10 of 18 results
- Karin Sipido (Responsible)
- Matthew Amoni (Member)
- Konstantinos Chatzieleftheriadis (Member)
- Joshua Jeen Tung Chung (Member)
- Maarten De Smet (Member)
- Kateryna Demydenko (Member)
- Rosa Donate Puertas (Member)
- Eef Dries (Member)
- Seyedehsamaneh Ekhteraeitousi (Member)
- David Fajardo (Member)
Projects
1 - 10 of 59
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Interventional X-ray system equipped with 3D rotational angiography for cardiovascular research in preclinical large animal models.From1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Cell-cell interactions and the role of tissue microarchitecture in cardiac arrhythmias after myocardial infarctionFrom19 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Cell-cell interactions and the role of tissue microarchitecture in cardiac arrhythmias after myocardial infarctionFrom15 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Second and Third Harmonics, a dynamic and Label-free imaging technique to study (bio)-polymers and cellular structuresAcronym: STHar-LiteFrom1 Oct 2021 → TodayFunding: BOF - projects
- Understanding the vulnerability of the ageing heartFrom1 Oct 2021 → TodayFunding: BOF - projects, Fund Recuperation Fiscal Exemption
- Investigating the Role and Opportunities of DNA methylation in the Ageing Heart.From1 Oct 2021 → TodayFunding: BOF - postdoctoral mandates
- Uncovering the role of the epigenome in atrial remodelling underlying the transition from paroxysmal to permanent atrial fibrillation by Single Cell OmicsFrom30 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Subcellular Ca2+ signalling microdomains regulating cardiomyocyte growth and functionFrom30 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Subcellular Ca2+ signalling microdomains regulating cardiomyocyte growth and functionFrom8 Sep 2021 → 15 Feb 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 336
- InsP3 regulated calcium signaling microdomains in the physiology and pathophysiology of ventricular cardiomyocytes(2022)
Authors: Kateryna Demydenko, LLewelyn Roderick, Karin Sipido
- Sexual dimorphism: increased sterol excretion leads to hypocholesterolaemia in female hyperbilirubinaemic Gunn rats(2022)
Authors: Onne Ronda
Pages: 1889 - 1911Number of pages: 23 - Killing in the name of: Reversing epigenetic silencing of ITPR3 to succumb cancer cells' resistance to chemotherapeutics(2022)
Authors: Nicolas Rosa, LLewelyn Roderick, Geert Bultynck
Number of pages: 2 - The cardiomyocyte firestarter-RyR clusters ignite their neighbours after augmentation of Ca2+ release by beta-stimulation(2022)
Authors: Kateryna Demydenko, LLewelyn Roderick
Number of pages: 4 - Human iPSC model reveals a central role for NOX4 and oxidative stress in Duchenne cardiomyopathy.(2022)
Authors: Robin Duelen, Domiziana Costamagna, Guillaume Gilbert, Katleen Desloovere, Catherine Verfaillie, Maurilio Sampaolesi
Pages: 352 - 368 - Cardioprotective effect of fingolimod against calcium paradox-induced myocardial injury in the isolated rat heart(2022)
Authors: Matthew Amoni
Pages: 134 - 141Number of pages: 8 - MSK-Mediated Phosphorylation of Histone H3 Ser28 Couples MAPK Signalling with Early Gene Induction and Cardiac Hypertrophy(2022)
Authors: Chandan Kadur Nagaraju, Karin Sipido, LLewelyn Roderick
Number of pages: 27 - Edward Carmeliet (1930-2021)-channelling scientific curiosity: a tribute from the ESC Working Group on Cardiac Cellular Electrophysiology(2021)
Authors: Karin Sipido
Pages: E171 - E173Number of pages: 3 - Hepatocyte-specific deletion of adipose triglyceride lipase (adipose triglyceride lipase/patatin-like phospholipase domain containing 2) ameliorates dietary induced steatohepatitis in mice(2021)
Authors: Onne Ronda
Pages: 125 - 139Number of pages: 15 - Inducing I-to,I-f and phase 1 repolarization of the cardiac action potential with a Kv4.3/KChIP2.1 bicistronic transgene(2021)
Authors: Eef Dries
Pages: 29 - 41Number of pages: 13