Laboratory of Cell Stress & Immunity
The Laboratory for Cell Stress & Immunity (CSI) focusses on following research themes: cancer immunology & immunotherapy (e.g. DC vaccines, immune-checkpoint blockers, chemo-immunotherapy), immunology of cancer cell death (e.g. programmed cell death like apoptosis, necrosis & necroptosis; stress responses, inflammation, immunity), stress or therapy-elicited immune-signalling pathways (e.g. type I interferons, NFkB signalling, phagocytosis, cytokines/chemokines, danger signals), immune cell biology (DCs, macrophages & T cells) and biomarkers for clinical immuno-oncology (e.g. computational immunology-driven analyses of CD8 T cell exhaustion/tumour immune-landscape & functional immunology of cancer patient's serum). Ultimately, our laboratory aims to specialize in reverse translational approaches to hasten basic and translational progress in the field of immuno-oncology.