Organisation
Laboratory of Computational Biology (VIB-KU Leuven)
Division
Research in the Laboratory of Computational Biology is focusing on gene and genome regulation, with applications in Drosophila and cancer, and on integrative genomics, developing computational methods for genomic data integration and analysis of next-generation sequence data.
Projects
41 - 50 of 64
- Unravelling Single Cell Gene Regulatory Networks in DrosophilaFrom10 May 2017 → 30 Sep 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- Deciphering the genetic program of epithelial cellsFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Deciphering the regulatory code underlying a common epigenomic survival switch in cancerFrom1 Jan 2017 → 31 Dec 2020Funding: Foundations, funds and other with scientific goal
- Exploiting enhancer logic and transcriptional networks to control phenotype switching in melanomaFrom1 Oct 2016 → 14 Dec 2020Funding: FWO Strategic Basic Research Grant, Private funding of national origin - undefined
- Towards petascale biocomputational sciencesFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- Regulatory genomics of normal cell differentiation and cancer cell subpopulations in the same tissue of origin.From1 Oct 2014 → 11 Jun 2021Funding: IWT personal funding - strategic basic research grants
- Drosophila Allograft Screen to Identify cis-Regulatory Variation in Cancer Genomes.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Using photoreceptor differentiation in Drosophila as a model system in order to decipher how a developmental program is encoded in a metazoan genome.From1 Oct 2013 → 30 Sep 2017Funding: BOF - Concerted Research Project from 1994
- Drosophila allograft screen to identify cis-regulatory variation in cancer genomes.From1 Oct 2013 → 9 May 2018Funding: IWT personal funding - strategic basic research grants
- Identification of cancer driver mutations in the non-coding genome by integrative genomics and regulome sequencing.From1 Jan 2013 → 31 Dec 2016Funding: Private funding of national origin - undefined
Publications
1 - 10 of 175
- HIGH-THROUGHPUT SEQUENCING OF THE HUMAN HEPATIC PROGENITOR CELL NICHE REVEALS DIFFERENT SIGNALLING PATHWAYS DEPENDING ON THE UNDERLYING CHRONIC LIVER DISEASE(2015)
Authors: Olivier Govaere, Jasper Wouters, Wouter Van Delm, R van Eijsden, An Ceulemans, Werner Van Steenbergen, Diethard Monbaliu, Frederik Nevens, Tania Roskams
Pages: S239 - S239 - Combined Proteomics and Transcriptomics Identifies Carboxypeptidase B1 and Nuclear Factor κB (NF-κB) Associated Proteins as Putative Biomarkers of Metastasis in Low Grade Breast Cancer(2015)
Authors: Hana Imrichova
Pages: 1814 - 1830 - The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene(2016)
Authors: Jasper Wouters, Joost van den Oord
- Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma(2020)
Authors: Jasper Wouters, Joost van den Oord
- Cancer stem cells in cutaneous melanoma(2009)
Authors: Jasper Wouters, Joost van den Oord, Hugo Vankelecom
Pages: 225 - 235 - Evidence for DNA-Binding Domain-Ligand-Binding Domain Communications in the Androgen Receptor(2012)
Authors: Christine Helsen, Vanessa Dubois, Annelien Verfaillie, Marc De Maeyer, Frank Claessens
Pages: 3033 - 3043 - CD45 antigen negativity in T-lineage ALL correlates with PTPRC mutation and sensitivity to a selective JAK inhibitor(2015)
Authors: Stein Aerts, Ellen Geerdens, Jan Cools
Pages: 884 - 7 - Plasma cells in primary melanoma. Prognostic significance and possible role of IgA(2016)
Authors: Francesca Bosisio, Jasper Wouters, Marguerite Stas, Joost van den Oord
Pages: 347 - 58 - BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis(2021)
Authors: Matteo Rossi, Chris Van den Haute, Maria Livia Sassano, Abhishek Garg, Francesca Bosisio, Jasper Wouters, Peter Vangheluwe, Wim Annaert, Johan Swinnen, Joost van den Oord, et al.
- A Functional In Situ Approach to TILs in Melanoma: A Critique on the Current Morphological Classification(2016)
Authors: Francesca Bosisio, Jasper Wouters, Nathalie Volders, Marguerite Stas, Joost van den Oord
Pages: 126A - 126A