Organisation
Laboratory of Molecullar and Cellular Therapy
Research Group
The focus of the Laboratory for Molecular and Cellular Therapy (LMCT) is directed towards the application of basic immunological knowledge and molecular biotechnology for the understanding, diagnosis and treatment of human diseases, including cancer, infectious disease and brain disease.
Current researchers
1 - 10 of 35 results
- Karine Breckpot (Responsible)
- Dorien Autaers (Member)
- Robin Maximilian Awad (Member)
- Jonathan Bastos (Member)
- Thomas Benoot (Member)
- Sanne Bevers (Member)
- Hannelore Ceuppens (Member)
- Céline Coelis (Member)
- Lien De Beck (Member)
- Kirsten De Ridder (Member)
Projects
1 - 10 of 11
- GEAR: Brussels Liver Research to Valorisation Alliance (B-Liver): Valorisation of VUB’s liver cell biology and toxicology expertise via a consortium focused on liver therapeutics, patient and consumer safety.From1 Jan 2020 → TodayFunding: IOF - technology concept exploration, IOF - mandates
- GEAR: Integrating a multimodal approach to address current challenges in immunotherapy (INTEGRAL)From1 Jan 2020 → TodayFunding: IOF - technology validation in real environment, IOF - mandates
- Eccentric: Enhancing the function of Cancer Countering Effector cells using Nanobodies Targeting Regulatory Immune CheckpointsFrom1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Combining targeted radionuclide therapy and cancer immunotherapy to advance precision medicine through innovation.From1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- A randomized phase II clinical trial in NSCLC combining SBRT and I.V. anti-PD-1 with or without I.T. anti-CTLA-4/anti-PD-L1 plus CD1c+ myDCFrom1 Oct 2019 → 30 Sep 2023Funding: FWO Applied Biomedical Research (TBM)
- Modulating epigenetic mechanisms to enhance cancer immunotherapy.From1 Oct 2018 → 30 Sep 2022Funding: FWO fellowships
- Target and explore the ‘X factor’ of the lung tumor microenvironment.From1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- Strategic Research Programme: Cancer Cell Targeting in Myeloma and Melanoma (MyMe)From1 Nov 2017 → TodayFunding: University - Project driven research
- Evaluating a Combination of Immune-based Therapies to Achieve a Functional Cure of HIV Infection (HIVACAR)From1 Jan 2017 → 30 Jun 2022Funding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing
- Rationally designed therapeutic vaccine against HIV-1 based on a novel formulation of nanoparticle-protected mRNAFrom1 Jan 2016 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
Publications
11 - 20 of 333
- Aging-associated subpopulations of human CD8+ T-lymphocytes identified by their CD28 and CD57 phenotypes(2015)
Authors: Oscar Onyema, Rose Njemini, Louis Nuvagah Forti, Ivan Bautmans, Joeri L Aerts, Marc De Waele, Tony Mets
Pages: 494-502 - Viral clade is associated with severity of symptomatic genotype 3 Hepatitis E virus infections in Belgium, 2010-2018(2023)
Authors: Michael Peeters, Julie Schenk, Thomas De Somer, Tania Roskams, Tatjana Locus, Sofieke Klamer, Lorenzo Subissi, Vanessa Suin, Jean Delwaide, Peter Stärkel, et al.
Pages: 67-77 - Successful (neo)adjuvant BRAF-targeted therapy in a patient with locally advanced BRAF V600E mutant melanoma(2015)
Authors: Teofila Seremet, Danielle Lienard, Mariano Suppa, Anne-Laure Trepant, Sandrine Rorive, Erwin Woff, Nicolas Cuylits, Yanina Jansen, Max Schreuer, Veronique Del Marmol, et al.
Pages: 180-183 - Immunomodulatory drugs: new developments(2013)
Authors: Karel Fostier
Pages: 21-28 - The journey of in vivo virus engineered dendritic cells from bench to bedside(2018)
Authors: Cleo Goyvaerts, K Breckpot
Pages: 2052 - ESMO consensus conference recommendations on the management of metastatic melanoma(2020)
Authors: U Keilholz, Paolo A Ascierto, R Dummer, Christophe Robert, Paul Lorigan, A van Akkooi, Ana Arance, Christian U Blank, Vanna Chiarion Sileni, M Donia, et al.
Pages: 1435-1448 - Phosphorylated STAT3 physically interacts with NPM and transcriptionally enhances its expression in cancer(2015)
Authors: Zhuo Ren, Joeri L Aerts, Joeri Pen, Carlo Heirman, K Breckpot, Jacques De Grève
Pages: 1650-1657 - Phase I Study of [68Ga]Ga-Anti-CD206-sdAb for PET/CT Assessment of Protumorigenic Macrophage Presence in Solid Tumors (MMR Phase I)(2023)
Authors: Odrade Gondry, Catarina Xavier, Laurens Raes, Johannes Heemskerk, Nick Devoogdt, Hendrik Everaert, K Breckpot, Q Lecocq, Lore Decoster, Christel Fontaine, et al.
Pages: 1378-1384 - Comparative analysis of antibodies to xCT (Slc7a11)(2016)
Authors: Joeri Van Liefferinge, Eduard Bentea, Thomas Demuyser, Giulia Albertini, Virginie Follin-Arbelet, Silvia Holmseth, Ellen Merckx, Hideyo Sato, Joeri L Aerts, Ilse Smolders, et al.
Pages: 1015-1032 - A PDGFRβ-based score predicts significant liver fibrosis in patients with chronic alcohol abuse, NAFLD and viral liver disease(2019)
Authors: Joeri Lambrecht, Stefaan Verhulst, Inge Mannaerts, Jan-Peter Sowa, Jan Best, Ali Canbay, Hendrik Reynaert, Leo A van Grunsven
Pages: 501-512