Organisation
Laboratory of Molecullar and Cellular Therapy
Research Group
The focus of the Laboratory for Molecular and Cellular Therapy (LMCT) is directed towards the application of basic immunological knowledge and molecular biotechnology for the understanding, diagnosis and treatment of human diseases, including cancer, infectious disease and brain disease.
Current researchers
1 - 10 of 35 results
- Karine Breckpot (Responsible)
- Dorien Autaers (Member)
- Robin Maximilian Awad (Member)
- Jonathan Bastos (Member)
- Thomas Benoot (Member)
- Sanne Bevers (Member)
- Hannelore Ceuppens (Member)
- Céline Coelis (Member)
- Lien De Beck (Member)
- Kirsten De Ridder (Member)
Projects
1 - 10 of 11
- GEAR: Brussels Liver Research to Valorisation Alliance (B-Liver): Valorisation of VUB’s liver cell biology and toxicology expertise via a consortium focused on liver therapeutics, patient and consumer safety.From1 Jan 2020 → TodayFunding: IOF - technology concept exploration, IOF - mandates
- GEAR: Integrating a multimodal approach to address current challenges in immunotherapy (INTEGRAL)From1 Jan 2020 → TodayFunding: IOF - technology validation in real environment, IOF - mandates
- Eccentric: Enhancing the function of Cancer Countering Effector cells using Nanobodies Targeting Regulatory Immune CheckpointsFrom1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Combining targeted radionuclide therapy and cancer immunotherapy to advance precision medicine through innovation.From1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- A randomized phase II clinical trial in NSCLC combining SBRT and I.V. anti-PD-1 with or without I.T. anti-CTLA-4/anti-PD-L1 plus CD1c+ myDCFrom1 Oct 2019 → 30 Sep 2023Funding: FWO Applied Biomedical Research (TBM)
- Modulating epigenetic mechanisms to enhance cancer immunotherapy.From1 Oct 2018 → 30 Sep 2022Funding: FWO fellowships
- Target and explore the ‘X factor’ of the lung tumor microenvironment.From1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- Strategic Research Programme: Cancer Cell Targeting in Myeloma and Melanoma (MyMe)From1 Nov 2017 → TodayFunding: University - Project driven research
- Evaluating a Combination of Immune-based Therapies to Achieve a Functional Cure of HIV Infection (HIVACAR)From1 Jan 2017 → 30 Jun 2022Funding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing
- Rationally designed therapeutic vaccine against HIV-1 based on a novel formulation of nanoparticle-protected mRNAFrom1 Jan 2016 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
Publications
31 - 40 of 333
- F-18-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma(2020)
Authors: Annie Wong, Jason Callahan, M Keyaerts, Bart Neyns, Johanna Mangana, Susanne Aberle, Alan Herschtal, Sonia Fullerton, Donna Milne, Amir Iravani, et al.
- Modelling fatty liver disease with mouse liver-derived multicellular spheroids(2022)
Authors: Elise Anne van Os, Laura Cools, Nathalie Eysackers, Karolina Szafranska, Ayla Smout, Stefaan Verhulst, Hendrik Reynaert, Peter McCourt, Inge Mannaerts, Leo A van Grunsven
- Association of homogeneous inflamed gene signature with a better outcome in patients with metastatic melanoma treated with MAGE-A3 immunotherapeutic(2018)
Authors: Jean-François Baurain, Caroline Robert, Laurent Mortier, Bart Neyns, Florent Grange, Céleste Lebbe, Fernando Ulloa-Montoya, Pedro Miguel De Sousa Alves, Marc Gillet, Jamila Louahed, et al.
- Turn Back the TIMe(2018)
Authors: R M Awad, Y De Vlaeminck, Johannes Maebe, Cleo Goyvaerts, K Breckpot
Pages: 1977 - Assessing Tumor-Infiltrating Lymphocytes in Breast Cancer(2022)
Authors: Hanne Locy, Stefaan Verhulst, Wilfried Cools, Wim Waelput, Stefanie Brock, Louise Cras, Ann Schiettecatte, Jan Jonckheere, Leo A van Grunsven, Marian Vanhoeij, et al.
Pages: 1-13 - Choriocapillaris Assessment In Patients Under Mek-Inhibitor Therapy For Cutaneous Melanoma(2021)
Authors: Giuseppe Fasolino, G Awada, Jorgos Socrates Koulalis, Bart Neyns, Peter Van Elderen, Robert Kuijpers, Pieter Nelis, Marcel Ten Tusscher
Pages: 765-771 - Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma(2015)
Authors: Ines Chevolet, Reinhart Speeckaert, Max Schreuer, Bart Neyns, Olga Krysko, Claus Bachert, Mireille Van Gele, Nanja van Geel, Lieve Brochez
- ESMO consensus conference recommendations on the management of metastatic melanoma(2020)
Authors: U Keilholz, Paolo A Ascierto, R Dummer, Christophe Robert, Paul Lorigan, A van Akkooi, Ana Arance, Christian U Blank, Vanna Chiarion Sileni, M Donia, et al.
Pages: 1435-1448 - The journey of in vivo virus engineered dendritic cells from bench to bedside(2018)
Authors: Cleo Goyvaerts, K Breckpot
Pages: 2052 - Intratumoral Delivery of TriMix mRNA Results in T-cell Activation by Cross-Presenting Dendritic Cells(2016)
Authors: Sandra Van Lint, Dries Renmans, Katrijn Broos, Lode Goethals, Sarah Maenhout, Daphné Benteyn, Cleo Goyvaerts, Stephanie Du Four, Kevin Van der Jeught, Lukasz Bialkowski, et al.
Pages: 146-156