Organisation
Laboratory of Molecullar and Cellular Therapy
Research Group
The focus of the Laboratory for Molecular and Cellular Therapy (LMCT) is directed towards the application of basic immunological knowledge and molecular biotechnology for the understanding, diagnosis and treatment of human diseases, including cancer, infectious disease and brain disease.
Current researchers
1 - 10 of 35 results
- Karine Breckpot (Responsible)
- Dorien Autaers (Member)
- Robin Maximilian Awad (Member)
- Jonathan Bastos (Member)
- Thomas Benoot (Member)
- Sanne Bevers (Member)
- Hannelore Ceuppens (Member)
- Céline Coelis (Member)
- Lien De Beck (Member)
- Kirsten De Ridder (Member)
Projects
1 - 10 of 11
- GEAR: Brussels Liver Research to Valorisation Alliance (B-Liver): Valorisation of VUB’s liver cell biology and toxicology expertise via a consortium focused on liver therapeutics, patient and consumer safety.From1 Jan 2020 → TodayFunding: IOF - technology concept exploration, IOF - mandates
- GEAR: Integrating a multimodal approach to address current challenges in immunotherapy (INTEGRAL)From1 Jan 2020 → TodayFunding: IOF - technology validation in real environment, IOF - mandates
- Eccentric: Enhancing the function of Cancer Countering Effector cells using Nanobodies Targeting Regulatory Immune CheckpointsFrom1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Combining targeted radionuclide therapy and cancer immunotherapy to advance precision medicine through innovation.From1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- A randomized phase II clinical trial in NSCLC combining SBRT and I.V. anti-PD-1 with or without I.T. anti-CTLA-4/anti-PD-L1 plus CD1c+ myDCFrom1 Oct 2019 → 30 Sep 2023Funding: FWO Applied Biomedical Research (TBM)
- Modulating epigenetic mechanisms to enhance cancer immunotherapy.From1 Oct 2018 → 30 Sep 2022Funding: FWO fellowships
- Target and explore the ‘X factor’ of the lung tumor microenvironment.From1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- Strategic Research Programme: Cancer Cell Targeting in Myeloma and Melanoma (MyMe)From1 Nov 2017 → TodayFunding: University - Project driven research
- Evaluating a Combination of Immune-based Therapies to Achieve a Functional Cure of HIV Infection (HIVACAR)From1 Jan 2017 → 30 Jun 2022Funding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing
- Rationally designed therapeutic vaccine against HIV-1 based on a novel formulation of nanoparticle-protected mRNAFrom1 Jan 2016 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
Publications
41 - 50 of 333
- Assessing Tumor-Infiltrating Lymphocytes in Breast Cancer(2022)
Authors: Hanne Locy, Stefaan Verhulst, Wilfried Cools, Wim Waelput, Stefanie Brock, Louise Cras, Ann Schiettecatte, Jan Jonckheere, Leo A van Grunsven, Marian Vanhoeij, et al.
Pages: 1-13 - Turn Back the TIMe(2018)
Authors: R M Awad, Y De Vlaeminck, Johannes Maebe, Cleo Goyvaerts, K Breckpot
Pages: 1977 - Theranostics in immuno-oncology using nanobody derivatives(2019)
Authors: Q Lecocq, Y De Vlaeminck, Heleen Hanssens, Matthias D'Huyvetter, G Raes, Cleo Goyvaerts, M Keyaerts, Nick Devoogdt, K Breckpot
Pages: 7772-7791 - Successful (neo)adjuvant BRAF-targeted therapy in a patient with locally advanced BRAF V600E mutant melanoma(2015)
Authors: Teofila Seremet, Danielle Lienard, Mariano Suppa, Anne-Laure Trepant, Sandrine Rorive, Erwin Woff, Nicolas Cuylits, Yanina Jansen, Max Schreuer, Veronique Del Marmol, et al.
Pages: 180-183 - Argon Plasma Coagulation as a Treatment of Multiple Esophageal Papillomata in a Girl with Goltz Syndrome(2019)
Authors: Koen Huysentruyt, Karolien Van De Maele, Bruno Hauser, Hendrik Reynaert, Fazia Mana, Yvan Vandenplas
Pages: e13-e13 - Choriocapillaris Assessment In Patients Under Mek-Inhibitor Therapy For Cutaneous Melanoma(2021)
Authors: Giuseppe Fasolino, G Awada, Jorgos Socrates Koulalis, Bart Neyns, Peter Van Elderen, Robert Kuijpers, Pieter Nelis, Marcel Ten Tusscher
Pages: 765-771 - Radiolabeled single-domain antibodies as a means to evoke and monitor immunological responses in malignant lesions(2023)
Authors: T Ertveldt, K Breckpot, Matthias D'Huyvetter, M Keyaerts, Nick Devoogdt
Number of pages: 177 - Applications for quantitative measurement of BRAF V600 mutant cell-free tumor DNA in the plasma of patients with metastatic melanoma(2016)
Authors: Max Schreuer, Geert Meersseman, Sari Van Den Herrewegen, Yanina Jansen, Teofila Seremet, Ambre Bott, Ines Chevolet, Sofie Wilgenhof, Geert Maertens, Bart Neyns
Pages: 157-163 - Focal radiation necrosis of the brain in patients with melanoma brain metastases treated with pembrolizumab(2018)
Authors: Stephanie Du Four, Yanina Jansen, Alex Michotte, A Vanbinst, Robbe Van den Begin, Johnny Duerinck, Bart Neyns
Pages: 4870-4879 - Preclinical evaluation of an mRNA HIV vaccine combining rationally selected antigenic sequences and adjuvant signals (HTI-TriMix)(2017)
Authors: A.C. Guardo, Patrick Tjok Joe, L Miralles, M.E. Bargallo, B Mothe, Ahmet Krasniqi, Carlo Heirman, F Garcia, Kris Thielemans, C Brander, et al.
Pages: 321-332