Organisation
Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven)
Division
The Lab of Molecular Oncology and Angiogenesis aims to shed light on the genetic and molecular mechanisms that regulate vessel shape remodeling and endothelial cell fate, with the overall aim of defining alternative therapeutic opportunities to improve anti-cancer therapy, as well as therapeutic angiogenesis for revascularization of ischemic tissues.
Projects
51 - 60 of 69
- The neurovascular link: an unexpectedly important role of metabolism.From1 Oct 2014 → 30 Sep 2021Funding: BOF - Methusalem
- GLUD1 inhibition promotes macrophage-mediated glutamine release, enhancing satellite cell activation and muscle regenerationFrom2 Sep 2014 → 20 Jun 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Assessing the influence of weight and nutrition on recovery and quality of life after esophagectomy for cancerFrom1 Sep 2014 → 1 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Identification of candidate biomarkers of intrinsic and acquired resistance to anti-angiogenic agents in metastatic colorectal cancer.From1 Jan 2013 → 31 Dec 2014Funding: Private funding of national origin - undefined
- Unraveling the role of Neuropilin 1 in tumor-associated macrophages : implications for therapy.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- The development of a proteomics procedure for the analysis of formalin-fixed paraffin-embedded tissue with the purpose of use in clinical studies.From1 Oct 2012 → 31 Dec 2017Funding: IWT personal funding - strategic basic research grants, BOF - Doctoral projects
- Role of PHD2 in cancer: PBP1 as new hub in the understanding of hypoxia driven-tumorigenesis.From1 Oct 2012 → 30 Sep 2015Funding: FWO fellowships
- Wordkstation for high speed and resolution imaging of living animals by confocal multiphoton laser scanning microscopy.From28 Jun 2012 → 27 Dec 2018Funding: Hercules - Small and Medium size research infrastructure
- Unraveling new molecular pathways in the oxygen sensing machinery.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
- The role of PHD mediated suppression of NF-kB signaling in tumor inflammation.From1 Oct 2011 → 5 Feb 2017Funding: FWO fellowships
Publications
1 - 10 of 311
- Modulating chitosan-PLGA nanoparticle properties to design a co-delivery platform for glioblastoma therapy intended for nose-to-brain route(2020)
Authors: Natalia N Ferreira, Sara Granja, Fernanda Boni, Fabiola G Prezotti, Leonardo MB Ferreira, Beatriz SF Cury, Rui M Reis, Fatima Baltazar, Maria Palmira D Gremiao
Pages: 1729 - 1747 - Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cells(2017)
Authors: Ana Ferreira de Oliveira, Sandra I Anjo, Joana Vieira de Castro, Sofia C Serra, Antonio J Salgado, Bruno Manadas, Bruno M Costa
- PD-1/PD-L1 immune checkpoint inhibitors in neoadjuvant therapy for solid tumors (Review)(2023)
Authors: Shikang Zhao
- A NEW ROLE FOR MMP-10 IN PATIENTS WITH PERIPHERAL ARTERY DISEASE AND EXPERIMENTAL ARTERIAL ISCHEMIA(2014)
Authors: Max Mazzone
Pages: E161 - E161 - The impact of hypoxia on tumor-associated macrophages(2016)
Authors: Anne-Theres Henze, Max Mazzone
Pages: 3672 - 3679 - Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia (vol 12, 435, 2021)(2021)
Authors: Germana Zaccagnini, Simona Greco, Marialucia Longo, Biagina Maimone, Christine Voellenkle, Paola Fuschi, Matteo Carrara, Pasquale Creo, Davide Maselli, Mario Tirone, et al.
- Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability(2022)
Authors: Max Mazzone
- The anti-proliferative effect of L-carnosine correlates with a decreased expression of hypoxia inducible factor 1 alpha in human colon cancer cells(2014)
Authors: Max Mazzone
- Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis(2017)
Authors: Ward Celus, Manuel Ehling, Max Mazzone
Pages: 2842 - 2854 - Understanding Metal Dynamics Between Cancer Cells and Macrophages: Competition or Synergism?(2020)
Authors: Max Mazzone