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Patent

3,4-diaminobenzenesulfonamide derivatives for inhibiting cell death

The present invention relates to a novel class of compounds having the structure of formula (I) and pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof. These compounds inhibit or reduce the non-apoptotic cell death forms ferroptosis and/or oxytosis rendering them useful for the treatment of various conditions disclosed herein.
Patent Publication Number: EP3218357
Year filing: 2020
Year approval: 2020
Year publication: 2020
Status: Assigned
Technology domains: Pharmaceuticals
Validated for IOF-key: Yes
Attributed to: Associatie Universiteit & Hogescholen Antwerpen, Associatie Universiteit Gent