Methods for diagnosing ovarian cancer

The invention relates to in vitro methods of distinguishing, in a patient diagnosed with an ovarian tumour, between a benign ovarian cyst and malignant ovarian cancer, based on determining in a blood sample the amount of at least NK cells, total myeloid cells, myeloid-derived suppressor cells (MDSC), monocytic myeloid derived suppressor cells (mMDSC), and PDL1 positive monocytic myeloid derived suppressor cells (mMDSC-PDL1). The invention further relates to kits comprising reagents for the detection of NK cells, myeloid-derived suppressor cells (MDSC), monocytic myeloid derived suppressor cells (mMDSC), and PDL1 positive monocytic myeloid derived suppressor cells (mMDSC-PDL1).

Patent Publication Number: WO2020193403

Year filing: 2020

Year approval: 2021

Year publication: 2020

Status: Requested

Technology domains: Analysis of biological materials

Validated for IOF-key: Yes

Attributed to: Associatie KULeuven