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Project

Advanced Signal Processing for Magnetic Resonance Spectroscopy

The overall objective of the PhD project is to investigate and develop cutting-edge Magnetic Resonance Spectroscopic Imaging (MRSI) software eMRSI for quantification and imaging of metabolites. The PhD research work is focused on/ Automatic Statistical Semi-Parametric Estimation/, encompassing novel, advanced signal processing and experimental design for metabolite quantification, properly accounting for the nuisance signals of water, macromolecules, and lipids.
 
In particular, two specific MRS quantification software packages will be integrated for acquiring improved results using prior knowledge of the metabolites and molecules that are present in healthy brain and brain tumors. Attention will be paid to optimizing of the baseline approach, robustifying semi-parametric estimation via regularization and quantifying parameter uncertainty.
Date:10 Jan 2008 →  29 Nov 2011
Keywords:Signal processing
Disciplines:Other engineering and technology
Project type:PhD project