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Project

Differential effects of androgens and estrogens ont he hyperthrophy and atrophy signals in the aging male skeletal muscle

This project aims to investigate the effects of androgens and estrogens on the atrophy and hypertrophy signalling pathways in skeletal muscle of young and aging males. According to the hypothesis, the decline in adrogens in the aging male activates atrophy signals leading to sarcopenia, whereas increased androgen levels will activate the hypertrophy pathways.

Date:1 Feb 2010 →  30 Nov 2014
Keywords:testosterone, muscle atrophy, sarcopenia
Disciplines:Physiology, Orthopaedics, Endocrinology and metabolic diseases