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Project

Early detection of cognitive decline from EEG responses in AD risk group

Dementia, mainly caused by Alzheimer’s disease (AD), is a chronic life-shortening condition with a progressive impact on the patient's life. Besides AD, increased attention is currently paid to the cognitive spectrum spanning normal aging to AD. The EEG technique already showed its potential in discriminating patients with objective signs of cognitive decline (AD and mild cognitive impairment (MCI)) from healthy controls. In this project, we will use EEG to address the pathological changes underlying subjective cognitive decline (SCD) in which case the patient signals complaints without any clinical manifestation. We hypothesize that certain EEG components can be used to single out SCD subjects at high risk of AD development. When successful, the study can serve as a starting point for the development of an easy-to-use, inexpensive and non-invasive screening tool.
Date:1 Oct 2018 →  30 Sep 2023
Keywords:subjective cognitive decline, event-related potentials, screening tool, mild cognitive impairment, AD risk group
Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing