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Project
A functional genomics study in zebrafish to elucidate the role of thyroid hormones and deiodinases in early emryonic development.
The overall aim of the study is to determine the role of THs in embryonic development in zebrafish, and vertebrates in general, prior to the onset of embryonic thyroid gland activity. More specifically we want to show how changes in intracellular T3 availability as a result of knockdown of both activating Ds influences major developmental processes such as gastrulation, neurulation and organogenesis.
Date:1 Jan 2010 → 31 Dec 2013
Keywords:EMBRYOLOGY, DEVELOPMENTAL BIOLOGY
Disciplines:Animal biology, Genetics, Endocrinology and metabolic diseases, Veterinary medicine
Project type:Collaboration project