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Project
The impact of artesunateamodiaquine retreatment and specific malaria humoral immunity on recrudescent malaria infections.
We will compare, in a non-inferiority, randomised, controlled trial, in Congolese children under 5 years of age, the efficacy of ASAQ to quinine as a rescue treatment for uncomplicated P. falciparum malaria. Additionally, given the key role of humoral immunity in protecting against malaria, we will assess antibody levels to merozoite antigens and VSAs in Congolese children under 5 with uncomplicated malaria and their association with anti-malarial treatment outcome.
Date:1 Jan 2011 → 31 Dec 2013
Keywords:MALARIA, EPIDEMIOLOGY
Disciplines:Tropical medicine
Project type:Collaboration project