Integrated Bovine Tuberculosis Diagnostics Approach: Bio-inspired Approaches (RF 19/6337 ID4BT)

The overarching research question:

"Can we generate a proof-of-concept for improved diagnostics based on naturally prevalent biomolecules?"

More specifically, we will answer the following questions in:

WP2: "Can the heavy chain only antibodies directed against BTB in Alpacas be used as an affinity isolation/detection tool in BTB diagnostics?"

WP3: "Can the cell wall binding domains of endolysins isolated from Mycobacterium phage be used as an affinity isolation/detection tool in BTB diagnostics?