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Multivalent dual-responsive polymeric nanoparticles for targeted anti-cancer therapy

In this project we aim to develop a formulation that selectively delivers anti-cancer drugs to cancer cells while minimizing unwanted toxicity to healthy tissue. For this purpose we will encapsulate hydrophobic anti-cancer agents in polymeric nanoparticles thate are engineered with (1) targeting ligands to selectively bind to cancer cells and (2) stimuli-responsive properties to release their drug payload only after cellular uptake.

Date:1 Oct 2013  →  30 Sep 2017
Keywords:drug delivery, cancer, polymers
Disciplines:Biomaterials engineering, Morphological sciences, Oncology, Process engineering, Polymeric materials, Chemical product design and formulation