Quantum dot nanoparticles for live cell imaging and intracellular targeting.
This project is aimed at enabling fluorescent labeling of organelles in living cells by quantum dots. At the one hand, silica encapped quantum dots will be targeted to the cytosol by making use of a membrane-disruptive liposomal carrier. At the other hand, a new concept will be tested using thermoresponsive nanoparticles to enable endosomal escape to the cytosol.
- See also: The toxicity of nanomaterials.