< Back to previous page


Multiple organ dysfunction syndrome

Journal Contribution - Journal Article

Subtitle:infection or hypersensitivity reaction?

Anticonvulsant hypersensitivity syndrome is a potentially life-threatening delayed hypersensitivity reaction characterized by the triad of fever, rash and multiorgan involvement, which usually occurs within the first weeks of introduction of an antiepileptic drug. It mimics several life-threatening diseases, which makes it potentially difficult to recognize. We describe the case of a 6-year-old boy admitted with anticonvulsant hypersensitivity syndrome after the association of lamotrigine treatment with sodium valproic acid for reluctant epilepsy.

Journal: Eur J Em Med
ISSN: 0969-9546
Issue: 4
Volume: 17
Pages: 228-229
Publication year:2010
Keywords:Anticonvulsants/adverse effects, Child, Drug Hypersensitivity/diagnosis, Drug Therapy, Combination, Humans, Hypersensitivity, Delayed/chemically induced, Lamotrigine, Male, Multiple Organ Failure/chemically induced, Triazines/adverse effects, Valproic Acid/adverse effects