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Time to initiation of multidrug-resistant tuberculosis treatment and its relation with outcome in a high incidence district in Lima, Peru

Journal Contribution - Journal Article

OBJECTIVE: To determine the time from diagnosis to start of multidrug resistant tuberculosis (MDR TB) treatment in Lima, Peru.

METHODS: We studied new smear-positive TB adults that were started on MDR TB treatment or that were switched to it between June 2008 and December 2011.

RESULTS: Time from the first positive smear to MDR-TB treatment was >30 days in 35% (13/37) of patients. Among the 27% (24/88) of patients that switched to MDR-TB treatment, time from the last dose of a drug-susceptible regimen was >30 days.

CONCLUSION: Start of and switching to MDR TB treatment is still delayed.

Journal: Tropical Medicine and International Health
ISSN: 1360-2276
Issue: 3
Volume: 20
Pages: 322-325
Publication year:2015
Keywords:Adult, Antitubercular Agents, Drug Substitution, Female, Humans, Incidence, Male, Outcome Assessment (Health Care), Peru, Retrospective Studies, Time Factors, Tuberculosis, Multidrug-Resistant, Tuberculosis, Pulmonary