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Researcher

Alexander Neumann

  • Research Expertise  (University of Antwerp):Dr. Neumann currently studies the genetics of Alzheimer’s disease biomarkers, by examining rare genetic variants obtained from whole exome sequencing (WES). The work focuses on pleiotropic effects on multiple biomarkers, as well as mediation analyses to test whether genes influencing Alzheimer's risk do so by affecting biomarker levels. Dr. Neumann obtained a PhD in psychiatric epidemiology from Erasmus University Rotterdam. The PhD thesis focuses on the genetics and epigenetics of child psychopathology, as well as the co-occurrence of child psychiatric problems. Dr. Neumann has experience leading genome-wide (GWAS) and epigenome-wide association studies (EWAS) in international consortia, such as the The EArly Genetics and Lifecourse Epidemiology (EAGLE) and Pregnancy And Childhood Epigenetics (PACE) consortia. He also worked on white matter integrity in relation to general psychopathology in childhood, as well as on the genetics of cortisol.
  • Keywords  (University of Antwerp):PSYCHIATRIC GENETICS, CHILD PSYCHIATRY, EPIGENETICS, ALZHEIMER'S DISEASE, PSYCHOPATHOLOGY, EPIDEMIOLOGY, GENETIC EPIDEMIOLOGY, Biomedical sciences (incl. biochemistry)
  • Research techniques  (University of Antwerp):Dr. Neumann has experience performing genome-wide and epigenome-wide association studies of complex traits, as well as analyzing whole exome sequencing data. Other techniques expertise include the computation and use of polygenic risk scores, structural equation modelling and analysis of longitudinal data, such as repeated measures of DNA methylation.
  • Users of research expertise  (University of Antwerp):Potential users are researchers, who wish to collaborate on genetic studies of Alzheimer's disease and related phenotypes, for example for replication or meta-analysis.

Affiliations

Publications

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