Researcher
Alfons Verbruggen
- Disciplines:Medicinal products, Biomarker discovery and evaluation, Drug discovery and development, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Faculty of Pharmaceutical Sciences (Faculty)
Member
From1 Oct 2020 → Today - Radiopharmaceutical Research (Division)
Member
From1 Oct 1999 → 30 Sep 2019
Projects
1 - 10 of 10
- translational study of the modulation of fosfodiesterase type 10A expression by dopaminergic neurotransmission using molecular imagingFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- Oncocidia_the novel anticancer therapy: phase 0 clinical study.From1 Jan 2013 → 31 Dec 2013Funding: IOF - Industrial Research Fund
- Development and evaluation of PET ligands for the in vivo visualisation of phosphodiesterase type 5 (PDE5).From1 Jan 2012 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
- Synthesis and biological evaluation of carbon-11 and fluorine-18 labelled P2X7-receptor ligands for diagnosis of neurological diseases using positron emission tomographyFrom1 Oct 2011 → 30 Sep 2015Funding: FWO fellowships
- In vivo molecular imaging research (IMIR).From1 Nov 2010 → 31 Oct 2018Funding: BOF - Concerted Research Project from 1994
- Molecular and functional imaging as a pivotal tool for translational medicine in the field of neuroscience and oncology: a platform creating a bridge between basic research, clinical development and industrial application.From1 Oct 2010 → 30 Sep 2014Funding: IOF - Industrial Research Fund
- Preclinical validation and first in man study of PET radioligands for the cannabinoidreceptor type 2.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- Synthesis and (pre)clinical evaluation of PET radioligands for in vivo visualization of phosphodiesterase 10, an enzyme involved in neurological and psychiatric disorders.From1 Oct 2009 → 30 Sep 2010Funding: BOF - Other initiatives
- Development of a radiolabelled probes for the in vivo visualisation of the TRPV1 receptor with PETFrom1 Oct 2008 → 24 Jan 2013Funding: IWT personal funding - strategic basic research grants
- Anti-kanker therapie versterkt door kleine radioactief gelabelde compounds met affiniteit voor necrosis (sRALNAC): een Prrof-of-Principle experiment ter ondersteuning van een nieuw patent aanvraag.From1 Jul 2008 → 30 Jun 2009Funding: IOF - Industrial Research Fund
Publications
111 - 120 of 124
- Synthesis, Characterization and Satiety in Rats of PEG10kDa-CCK-10 and (Radio)Iodinated PEG10kDa-CCK-10(2009)
Authors: Fabian Léon-Tamariz, Isabelle Verbaeys, Maurits Van Boven, Marcel De Cuyper, Johan Buyse, Elke Clynen, Eveline Lescrinier, Alfons Verbruggen, Marnix Cokelaere
Pages: 177 - 183 - The Presence of Ethanol in Radiopharmaceutical Injections(2008)
Authors: Kim Serdons, Alfons Verbruggen, Guy Bormans
Pages: 2071 - 2071 - Guideline to regulations for radiopharmaceuticals in early phase clinical trials in the EU(2008)
Authors: Alfons Verbruggen
Pages: 2144 - 2151 - Labelling and biological evaluation of [C-11]methoxy-Sch225336: a radioligand for the cannabinoide-type 2 receptor(2008)
Authors: Nele Evens, Roger Busson, Koen Van Laere, Alfons Verbruggen, Guy Bormans
Pages: 793 - 800 - Development of Tc-99m-thioflavin-T derivatives for detection of systemic amyloidosis(2008)
Authors: Kim Serdons, T Verduyckt, Bernard Cleynhens, Guy Bormans, Alfons Verbruggen
Pages: 357 - 367 - Development of Tc-99m-thioflavin-T derivatives for detection of systemic amyloidosis(2008)
Authors: Kim Serdons, Guy Bormans, Alfons Verbruggen
Pages: 357 - 367 - Preliminary in vivo evaluation of a novel 99mTc-labeled HYNIC-cys-annexin A5 as an apoptosis imaging agent(2008)
Authors: Marijke De Saint-Hubert, Kathleen Vunckx, Johan Nuyts, Guy Bormans, Yicheng Ni, Alfons Verbruggen
Pages: 3794 - 3798 - Efficient purification and metabolite analysis of radiotracers using high-performance liquid chromatography and on-line solid-phase extraction(2008)
Authors: Satish Kumar Chitneni, Kim Serdons, Nele Evens, Humphrey Fonge, Sofie Celen, Christophe Deroose, Zeger Debyser, Luc Mortelmans, Alfons Verbruggen, Guy Bormans
Pages: 323 - 331 - Synthesis and biological evaluation of carbon-11-labeled acyclic derivatives of and furo[2,3-d]pyrimidine bicyclic nucleoside analogues (BCNAs) for structure-brain uptake relationship study of BCNA tracers(2008)
Authors: Satish Kumar Chitneni, Jan Balzarini, Sofie Celen, Natalia Dyubankova, Alfons Verbruggen, Guy Bormans
Pages: 159 - 166 - Synthesis and evaluation of F-18- and C-11-labeled phenyl-galactopyranosides as potential probes for in vivo visualization of LacZ gene expression using positron emission tomography(2008)
Authors: Sofie Celen, Christophe Deroose, Satish Kumar Chitneni, Rik Gijsbers, Zeger Debyser, Luc Mortelmans, Alfons Verbruggen, Guy Bormans
Pages: 441 - 449
Patents
1 - 4 of 4