Researcher
Annelii Ny
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Molecular Biodiscovery (Division)
Member
From1 Apr 2013 → 31 Dec 2022
Projects
1 - 5 of 5
- Building towards a patent - Exploitation of the killifish R&D platform to combat neurodegenerative diseasesFrom1 Feb 2024 → TodayFunding: IOF - mandates
- PHGDH-ASM: Phosphoglycerate dehydrogenase (PHGDH) activators as novel antiseizure medications (ASM) with dual mode of actionFrom1 Oct 2022 → TodayFunding: IOF - technology validation in lab
- Zebrafish platform for neuroactive drug discovery and safety assessmentFrom1 Jan 2019 → 31 Dec 2020Funding: IOF - technology validation in lab
- Use of fluorescent probes to study pharmacokinetics in zebrafish (Danio rerio) embryos and larvaeFrom12 Dec 2017 → 19 Nov 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Zebrafish platform for drug discovery and safety testingFrom1 Jan 2016 → TodayFunding: IOF - mandates, IOF - Industrial Research Fund
Publications
1 - 10 of 24
- Use of fluorescent probes to study pharmacokinetics in zebrafish (Danio rerio) embryos and larvae(2021)
Authors: Marlly Guarin, Peter de Witte, Pieter Annaert, Annelii Ny
- Pre-validation of choriogenin H transgenic medaka eleutheroembryos as a quantitative estrogenic activity test method(2021)
Authors: Peter de Witte, Annelii Ny
- Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration(2021)
Authors: Marlly Guarin, Ruben Faelens, Deirdre Cabooter, Pieter Annaert, Peter de Witte, Annelii Ny
- Infection of zebrafish larvae with human norovirus and evaluation of the in vivo efficacy of small-molecule inhibitors(2021)
Authors: Jana Van Dycke, Arno Cuvry, Annelii Ny, Peter de Witte, Johan Neyts, Joana Duarte Da Rocha Pereira
Pages: 1830 - + - Nephrotoxic Effects in Zebrafish after Prolonged Exposure to Aristolochic Acid(2020)
Authors: Xixin Wang, Arianna Giusti, Annelii Ny, Peter de Witte
- A robust human norovirus replication model in zebrafish larvae(2019)
Authors: Jana Van Dycke, Annelii Ny, Arno Cuvry, Erik Verbeken, Jelle Matthijnssens, Peter de Witte, Johan Neyts, Joana Duarte Da Rocha Pereira
- Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos(2019)
Authors: Arianna Giusti, Mélanie Mignot, Pieter Annaert, Annelii Ny, Deirdre Cabooter, Peter de Witte
- Bioassay-guided isolation of anti-seizure principles from Semen Pharbitidis using a zebrafish pentylenetetrazol seizure model(2019)
Authors: Maoxuan Liu, Daniëlle Copmans, Jo Sourbron, Annelii Ny, Peter de Witte, Walter Luyten
Pages: 130 - 134 - Methylated flavonoids as anti-seizure agents: Naringenin 4 ',7-dimethyl ether attenuates epileptic seizures in zebrafish and mouse models(2018)
Authors: Daniëlle Copmans, Gert Steurs, Yifan Zhang, Annelii Ny, Aleksandra Siekierska, Wim De Borggraeve, Wim Dehaen, Peter de Witte
Pages: 124 - 133 - Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish(2017)
Authors: Yifan Zhang, Michiel Vanmeert, Aleksandra Siekierska, Annelii Ny, Geert Callewaert, Eveline Lescrinier, Wim Dehaen, Peter de Witte
Patents
1 - 7 of 7
- Treatment of pharmacoresistant epilepsy (Inventor)
- Idebenone in the treatment of drug resistant epilepsy (Inventor)
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy with plinabulin or halimide or diketopiperazine derivatives (Inventor)
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy with plinabulin or halimide or diketopiperazine derivatives (Inventor)
- Treatment of epilepsy (Inventor)