Researcher
Bart De Spiegeleer
- Keywords:Pharmaceuticals
- Disciplines:In vitro testing, Non-clinical studies, Molecular medicine, Separation techniques, Spectrometry, Drug regulation, Medical systems biology not elsewhere classified
Affiliations
- Department of Pharmaceutical analysis (Department)
Member
From1 Oct 2003 → Today
Projects
1 - 10 of 21
- The role of the quorum sensing peptide PapRIV in regulating microglia.From1 Oct 2021 → TodayFunding: BOF - projects
- Development of a live biotherapeutic medicine against colorectal cancer metastasis.From1 Jan 2021 → 31 Dec 2023Funding: IOF - technology validation in lab
- The in vivo role of quorum sensing peptides in metastatic colorectal cancer.From1 Nov 2020 → 28 Feb 2021Funding: FWO Strategic Basic Research Grant
- The development of 68-gallium-NOTA-somatropin, a targeted radiopharmaceutical for the diagnosis of growth hormone receptor-positive cancers.From1 Nov 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Development of artemisinin-derived medicines to improve stability and pharmacokinetic propertiesFrom1 Oct 2020 → TodayFunding: BOF - doctoral mandates
- Controlled delivery of connexin43 mimetic peptide by nanocontainers for therapy of systemic inflammationFrom1 Oct 2018 → 31 Jul 2023Funding: BOF - Doctoral projects
- MSsmall: mass spectrometry for small organic moleculesFrom1 Feb 2017 → 30 Nov 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- 68Gallium- and 177Lutetium/NOTA-somatropin for imaging and treatment of GH-R expressing melanomaFrom1 Jan 2017 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- The presence of quorum sensing peptides in clinical samples: their biological role in oncology.From1 Jan 2017 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
- Development of in-vivo relevant dissolution systems for selected neglected-diseases medicinesFrom1 Aug 2014 → 30 Sep 2020Funding: BOF - Doctoral projects
Publications
11 - 20 of 304
- Statin intake and all-cause mortality among older nursing home residents(2022)
Authors: Anton De Spiegeleer, Jordi Van Migerode, Antoon Bronselaer, Evelien Wynendaele, Milan Peelman, Filip Vandaele, Geert Byttebier, Guy De Tré, Luc Belmans, Mike Sathekge, et al.
Pages: 407 - 411 - Adjunctive use of statins for COVID-19(2021)
Authors: Mike Sathekge, Geert Byttebier, Bart De Spiegeleer, Bo Saxberg, Veronica Ueckermann, Luc Belmans, Myriam Alexander, David Fedson
- Apoptosis imaging in oncology by means of positron emission tomography : a review(2021)
Authors: Christophe Van De Wiele, Sezgin Ustmert, Bart De Spiegeleer, Pieter-Jan De Jonghe, Mike Sathekge, Maes Alex
- Sustainability in drug discovery(2021)
Authors: Evelien Wynendaele, Christophe Furman, Bartosz Wielgomas, Per Larsson, Eelko Hak, Thomas Block, Serge Van Calenbergh, Nicolas Willand, Michal Markuszewski, Luke R. Odell, et al.
- Cov-MS : a community-based template assay for mass-spectrometry-based protein detection in SARS-CoV-2 patients(2021)
Authors: Bart Van Puyvelde, Katleen Van Uytfanghe, Olivier Tytgat, Laurence Van Oudenhove, Robbin Bouwmeester, Simon Daled, Sigrid Verhelst, Laura De Clerck, Laura Corveleyn, Sander Willems, et al.
Pages: 750 - 765 - Effects of backbone cyclization on the pharmacokinetics and drug efficiency of the orally active analgesic conotoxin cVc1.1(2021)
Authors: Aaron G. Poth, Francis C.K. Chiu, Sofie Stalmans, Brett R. Hamilton, Yen-Hua Huang, David M. Shackleford, Rahul Patil, Thao T. Le, Meng-Wei Kan, Thomas Durek, et al.
- Hospital mortality in COVID-19 patients in Belgium treated with statins, ACE inhibitors and/or ARBs(2021)
Authors: Geert Byttebier, Luc Belmans, Myriam Alexander, Bo E. H. Saxberg, Bart De Spiegeleer, Anton De Spiegeleer, Nick Devreker, Jens Van Praet, Karolien Vanhove, Reinhilde Reybrouck, et al.
Pages: 2841 - 2850 - Dietary muramidase degrades bacterial peptidoglycan to NOD-activating muramyl dipeptides and reduces duodenal inflammation in broiler chickens(2021)
Authors: Ya Wang, Evy Goossens, Venessa Eeckhaut, Estefania Pérez Calvo, Rual Lopez-Ulibarri, Irene Eising, Mikkel Klausen, Nathan Debunne, Bart De Spiegeleer, Richard Ducatelle, et al.
Pages: 641 - 651 - PapRIV : a BV-2 microglial cell activating quorum sensing peptide(2021)
Authors: Yorick Janssens, Nathan Debunne, Anton De Spiegeleer, Evelien Wynendaele, Marta Planas, Lidia Feliu, Alessandra Quarta, Christel Claes, Debby Van Dam, Peter Paul De Deyn, et al.
- MEK1/2 inhibition in murine heart and aorta after oral administration of refametinib supplemented drinking water(2020)
Authors: Felke Steijns, Nathalie Bracke, Marjolijn Renard, Julie De Backer, Patrick Sips, Nathan Debunne, Evelien Wynendaele, Frederick Verbeke, Bart De Spiegeleer, Laurence Campens
Patents
1 - 3 of 3