Researcher
Björn Menten
- Keywords:prenatal genetic testing, genomics, whole genome sequencing, long read sequencing, preimplantation genetic testing
- Disciplines:Epigenetics, Analysis of next-generation sequence data, Bioinformatics of disease, Bioinformatics data integration and network biology, Data visualisation and high-throughput image analysis, Ontologies, data curation and text mining, Development of bioinformatics software, tools and databases, Immunogenetics, Clinical genetics and molecular diagnostics, Medical epigenomics, Medical metagenomics, Medical genomics, Single-cell data analysis, Genetics, Structural bioinformatics and computational proteomics, Bioinformatics and computational biology not elsewhere classified
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Dean's Office of the Faculty of Medicine and Health Sciences (Administrative office)
Member
From1 Oct 2003 → 30 Sep 2005 - Department of Pediatrics and medical genetics (Department)
Member
From1 Feb 2003 → 30 Sep 2018
Projects
1 - 10 of 25
- Safety first: optimizing artificial oocyte creation through diploid cell haploidizationFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Nuclear Transfer for female-related infertility and mitochondrial diseasesFrom1 Oct 2023 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Application of the Nuclear Transfer technology to overcome female-related infertilityFrom1 Oct 2023 → TodayFunding: BOF - mobility
- Long-read sequencing for the detection of cryptic structural variation in patients with intellectual disability and congenital anomaliesFrom16 Sep 2023 → TodayFunding: BOF - doctoral mandates
- Detection of somatic mutations and disease-defining methylation patterns in brain tissue and cerebrospinal fluid of patients with non-acquired focal epilepsyFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Cofunding core facility - UGent NGS CoreFrom1 Jul 2022 → TodayFunding: BOF - research organisations
- Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine developmentFrom1 Jan 2021 → TodayFunding: BOF - projects
- Non-invasive prenatal screening for the presymptomatic detection of pregnancy complicationsFrom1 Jul 2020 → 30 Jun 2022Funding: IOF - technology validation in lab
- Precision medicine in inherited blindness using integrated omics in human and animal modelsFrom1 Jan 2020 → TodayFunding: BOF - projects
- In-depth comparison and feasibility assessment of an integrated pipeline for neoantigen identification and HLA ligandome sequencing in a clinical settingFrom1 Nov 2019 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant
Publications
11 - 20 of 47
- Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility(2021)Volume: 36
Authors: Bieke Bekaert, Annekatrien Boel, Mina Popovic, Panagiotis Stamatiadis, S M Chuva de Sousa Lopes, Petra De Sutter, Björn Menten, Dominic Stoop, Paul Coucke, Björn Heindryckx
Pages: 11 - 11 - Shallow whole-genome sequencing of plasma cell-free DNA accurately differentiates small from non-small cell lung carcinoma(2020)
Authors: Lennart Raman, Malaïka Van der Linden, Kim Van der Eecken, Karim Vermaelen, Ingel Demedts, Veerle Surmont, Ulrike Himpe, Franceska Dedeurwaerdere, Liesbeth Ferdinande, Yolande Lievens, et al.
- Unraveling complex structural variants of CEP78 leading to cone-rod dystrophy and hearing loss using long-read sequencing(2020)
Authors: Giulia Ascari, Nanna D. Rendtorff, Julie Jacob, Julie De Zaeytijd, Valerie Baumont, Marieke De Bruyne, Toon Rosseel, Mattias Van Heetvelde, Tim De Pooter, Wouter De Coster, et al.
Number of pages: 1 - Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia(2019)
Authors: Gayle P Pouliot, James Degar, Laura Hinze, Bose Kochupurakkal, Chau D Vo, Melissa A Burns, Lisa Moreau, Chirag Ganesa, Justine Roderick, Sofie Peirs, et al.
- PCR based target enrichment for variant confirmation, gene panels and multiplex PCR sample tracking in a whole exome sequencing workflow(2019)Volume: 27
Authors: Frauke Coppieters, Thalia Van Laethem, Matthias De Smet, Paul Coucke, Elfride De Baere, Kathleen Claes, Björn Menten, Jo Vandesompele, Steve Lefever
Pages: 1660 - 1661 - Two novel probands with Myhre syndrome identified through WES(2019)Volume: 27
Authors: Ilse Meerschaut, Aude Beyens, Wouter Steyaert, Riet De Rycke, Björn Menten, Katrien Bonte, Tine De Backer, Sandra Janssens, Fransiska Malfait, Joseph Panzer, et al.
Pages: 118 - 118 - Non-invasive prenatal testing (NIPT) : how to handle secondary findings of maternal chromosomal abnormalities(2019)Volume: 27
Authors: Machteld Baetens, Tom Sante, Sarah Vergult, M. De Smet, S. Janssens, Olivier Vanakker, Bert Callewaert, Bruce Poppe, Annelies Dheedene, Björn Menten
Pages: 24 - 24 - De novo missense variants in RAC3 cause a novel neurodevelopmental syndrome(2019)Volume: 179
Authors: M. Osundiji, G. Costain, B. Callewaert, H. Gabriel, T. Y. Tan, S. Walker, Björn Menten, A. Vanlander, S. Vergult, M. Snell, et al.
Pages: 739 - 739 - A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation(2019)
Authors: Simon Tavernier, V Athanasopoulos, PATRICK VERLOO, G Behrens, Jens Staal, Delfien Bogaert, Leslie Naesens, Marieke De Bruyne, Sofie Van Gassen, Eef Parthoens, et al.
- Circulating cell-free DNA for response evaluation of intravascular lymphoma(2019)
Authors: Dries Deeren, Malaïka Van der Linden, Franceska Dedeurwaerdere, Lien Deleu, Caressa Meert, Björn Menten, Jo Van Dorpe
Pages: 2021 - 2023