Researcher
Catherine Verfaillie
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → 30 Sep 2022
Infrastructure
1 - 1 of 1
- Platform for Next Generation Screening in Quantitative Biology & Drug Discovery (Consortium coordinator)
Projects
41 - 50 of 95
- An Integrated European 'Flagship' program: Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century.From1 Jan 2016 → 31 Dec 2021Funding: H2020 - Health, demographic change and wellbeing
- iPSC: Therapeutic target identification for FTD/ALS using human induced pluripotent stem cell modelsFrom1 Nov 2015 → 31 Oct 2019Funding: SBO (Strategic basic research)
- In search of novel working mechanisms of proteasome inhibitors in multiple myelomaFrom1 Oct 2015 → 13 Nov 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- RNA Based Gene Therapy In A Model Of RNA Based Gene Therapy In A Model Of Usher syndromeFrom9 Sep 2015 → 31 Dec 2021Funding: FWO fellowships
- Developing an in vivo humanized mouse model suitable for the study of hepatotropic viral infectionFrom15 Aug 2015 → 1 Feb 2021Funding: FWO fellowships
- 3D Liver Organoids: Modelling Host Hepatitis B Virus InteractionFrom1 Mar 2015 → 28 Feb 2017Funding: H2020 - Skills and Career Development (Marie Skłodowska-Curie) actions
- Inducing enhanced homing and ex vivo expansion of umbilical cord blood stem cells to allow engraftment in adult patients.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Humanized Immune Liver Mouse and 3D in vitro models for the study and therapy of liver disease.From1 Nov 2014 → 31 Oct 2018Funding: SBO (Strategic basic research)
- KU Leuven Stem Cell PlatformFrom1 Nov 2014 → 30 Sep 2016Funding: IOF - Industrial Research Fund
- Skeletal control of hematopoiesis: Impact of the stromal-vascular bone marrow niche in the support of fetal and adult hematopoiesisFrom1 Nov 2014 → 22 Jun 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 374
- Glycolytic state of aortic endothelium favors hematopoietic transition during the emergence of definitive hematopoiesis.(2024)
Authors: Catherine Verfaillie
Pages: eadh8478 - Spatially Self-Organized Three-Dimensional Neural Concentroid as a Novel Reductionist Humanized Model to Study Neurovascular Development(2024)
Authors: Yoke Chin Chai, San Kit To, Yingli Zhu, Ben van der Veer, Vincent Pasque, Catherine Verfaillie
- Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF-κВ and WNT Signaling(2024)
Authors: Jonathan Chui, Aneta Malesa, Paraskevi ATHANASOULI, Joris Vriens, Kian Koh, Catherine Verfaillie, Frederic Lluis Vinas
- Robotics-Driven Manufacturing of Cartilaginous Microtissues for Skeletal Tissue Engineering Applications(2024)
Authors: Isaak Decoene, Gabriele Nasello, Catherine Verfaillie, Liesbet Geris, Frank Luyten, Ioannis Papantoniou
Pages: 278 - 292 - Automated Generation of hiPSC-Derived Hepatic Progeny by Cost-Efficient Compounds(2023)
Authors: Kristof De Vos, Teresa Izuel Idoype, Pieter Annaert, Frederic Lluis Vinas, Catherine Verfaillie
Pages: 1076 - 1088 - Editorial: New insights of immune cells in cardiovascular and metabolic disorders(2023)
Authors: Catherine Verfaillie
- Engineering Neurovascular Organoids and Morphogen Gradients with 3D Printed Microfluidic Chips(2023)
Authors: Idris Salmon, Adrian Ranga, Catherine Verfaillie
- APEX1 Nuclease and Redox Functions are Both Essential for Adult Mouse Hematopoietic Stem and Progenitor Cells(2023)
Authors: Samantha Zaunz, Lukas Lauwereins, Kim De Keersmaecker, Catherine Verfaillie
Pages: 2052 - 2072 - From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions(2023)
Authors: Catherine Verfaillie
Pages: 283 - 299 - Genetically Engineered Triple MAPT-Mutant Human-Induced Pluripotent Stem Cells (N279K, P301L, and E10+16 Mutations) Exhibit Impairments in Mitochondrial Bioenergetics and Dynamics(2023)
Authors: Catherine Verfaillie
Patents
1 - 10 of 10
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Hydrogels for cell culture (Inventor)
- Nek6 inhibition to treat als and ftd (Inventor)
- Spheroidal self-assembled peptide hydrogels comprising cells (Inventor)
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Cell culture media for differentiation of stem cells into hepatocytes (Inventor)
- Methods for identifying activators and suppressors (Inventor)
- Stem cell aggregates and methods for making and using (Inventor)
- Cell therapy for myelodysplastic syndromes (Inventor)
- Optimized methods for differentiation of cells into cells with hepatocyte and hepatocyte progenitor phenotypes, cells produced by the methods, and methods for using the cells (Inventor)