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Researcher
Charles De Bock
- Disciplines:Systems biology
Affiliations
- Laboratory of Molecular Biology of Leukemia (VIB-KU Leuven) (Division)
Member
From1 Nov 2012 → 31 Dec 2019
Projects
1 - 1 of 1
- Cooperation of TLX3 with epigenetic changes in the development of T-cell acute lymphoblastic leukemiaFrom1 Oct 2018 → 20 Oct 2022Funding: FWO fellowships
Publications
11 - 20 of 32
- HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development(2018)
Authors: Charles De Bock, Sofie Demeyer, Sandrine Degryse, Delphine Verbeke, Marlies Vanden Bempt, Ellen Geerdens, Simon Bornschein, Rik Gijsbers, Jan Cools
Pages: 616 - 631 - miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense(2018)
Authors: Charles De Bock
Pages: 501 - 515 - JAK3 mutations and HOXA9 expression are important cooperating events in T-cell acute lymphoblastic leukemia(2018)
Authors: Charles De Bock, Jan Cools
- Mutant JAK3 signaling is increased by loss of wild type JAK3 or by acquiring secondary JAK3 mutations in T-ALL(2018)
Authors: Sandrine Degryse, Simon Bornschein, Charles De Bock, Marlies Vanden Bempt, Sofie Demeyer, Ellen Geerdens, Jan Cools
Pages: 421 - 425 - Protein interaction screening identifies SH3RF1 as a new regulator of FAT1 protein levels(2017)
Authors: Charles De Bock
Pages: 667 - 678 - Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors(2016)
Authors: Sofie Demeyer, Jolien De Bie, Sandrine Degryse, Ellen Geerdens, Anne Uyttebroeck, Nancy Boeckx, Charles De Bock, Jan Cools
Pages: 2642 - 2654 - CELL BIOLOGY A mitochondrial brake on vascular repair(2016)
Authors: Charles De Bock
Pages: 503 - 505 - Generation of the Fip1l1-Pdgfra fusion gene using CRISPR/Cas genome editing(2016)
Authors: Marlies Vanden Bempt, Sofie Demeyer, Ellen Geerdens, Charles De Bock, Jan Cools
Pages: 1913 - 1916 - Measures of success(2016)
Authors: Charles De Bock
Pages: 28 - 30 - Measures of success Reply(2016)
Authors: Charles De Bock
Pages: 29 - 29