Researcher
Claude Libert
- Keywords (Ghent University):sepsis
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Epigenetics, Animal genetics, Autoimmunity, Clinical genetics and molecular diagnostics, Immunogenetics, Innate immunity, Transplantation immunology, Genetics, Applied immunology, Gastro-enterology and hepatology not elsewhere classified, Genome structure and regulation, Quantitative genetics, Endocrinology and metabolic diseases not elsewhere classified
- See also: Claude Libert (Flanders Institute for Biotechnology)
Affiliations
- Libert Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Biomedical molecular biology (Department)
Member
From1 Oct 1996 → Today - Department of Plant Biotechnology and Bioinformatics (Department)
Member
From1 Jan 1993 → 30 Sep 1996
Projects
21 - 30 of 67
- A profound study of the mechanism and field of application of the increase of Glucocorticoid Receptor transcriptional activity by zinc. From1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Towards a substantial increase in therapeutic index of TNF From1 Jan 2016 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- A profound study of the pro-inflammatory activities of MMPs From1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Application of novel tools and insights to understand the exact role
of TNF in polymicrobial sepsis and to develop an efficient therapy.From1 Oct 2015 → 30 Sep 2020Funding: FWO fellowships
- Generation and detailed analysis of novel tools to study the importance of dimerization of the Glucocorticoid Receptor in inflammation.From1 Oct 2015 → 30 Sep 2019Funding: FWO fellowships
- Analysis of the effect of caloric restriction on the choroid plexus epithelial (CPE) cells that form the blood-cerebrospinal fluid barrier (BCSFB).From1 Oct 2015 → 30 Sep 2019Funding: FWO fellowships
- Search for new therapeutic strategies to treat Alzheimer's disease: development of an in vitro system for high throughput compound screening based on choroid plexus epithelium. From1 Jan 2015 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Generation and detailed analysis of novel tools to study the importance of dimerization of the Glucocorticoid Receptor in inflammation. From1 Jan 2015 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Effect of Helicobacter suis infection to the onset of neurodegenerative diseases in humans.From1 Oct 2014 → 30 Sep 2018Funding: BOF - Doctoral projects
- Optimisation of a aVB3 targeted Nanobodies for cancer therapy, cancer imaging and targeted delivery.From1 Jan 2014 → 31 Dec 2014Funding: Nonprofit institution or equivalents
Publications
1 - 10 of 205
- The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function(2023)
Authors: Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Charlotte Wallaeys, Louise Nuyttens, Joyca De Temmerman, Tino Hochepied, Sylviane Dewaele, et al.
- Mousepost 2.0, a major expansion of the resource(2023)
Authors: Steven Timmermans, Jolien Vandewalle, Claude Libert
Pages: 1652 - 1661 - Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF(2023)
Authors: Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Böhme, Laurentijn Tilleman, Imke Velghe, Valentina Pegoretti, Inge Van de Walle, Stephanie Sontag, et al.
Pages: 474 - 486 - Circulating cell-free DNA in health and disease : the relationship to health behaviours, ageing phenotypes and metabolomics(2023)
Authors: Laura Kananen, Mikko Hurme, Alexander Bürkle, Maria Moreno-Villanueva, Jürgen Bernhardt, Florence Debacq-Chainiaux, Beatrix Grubeck-Loebenstein, Marco Malavolta, Andrea Basso, Francesco Piacenza, et al.
Pages: 85 - 103 - Paneth cells as the cornerstones of intestinal and organismal health : a primer(2023)
Authors: Charlotte Wallaeys, Natalia Garcia Gonzalez, Claude Libert
- Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding(2022)
Authors: Steven Timmermans, Nicolette J.D. Verhoog, Kelly Van Looveren, Sylviane Dewaele, Tino Hochepied, Melanie Eggermont, Barbara Gilbert, Anne Boerema-de Munck, Tineke Vanderhaeghen, Joke Vanden Berghe, et al.
- Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements(2022)
Authors: Lovelace J. Luquette, Michael B. Miller, Zinan Zhou, Craig L. Bohrson, Yifan Zhao, Hu Jin, Doga Gulhan, Javier Ganz, Sara Bizzotto, Samantha Kirkham, et al.
Pages: 1564 - 1571 - Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets(2022)
Authors: Brecht Maertens, An Staes, Claude Libert, Onno C. Meijer
- Reprogramming of glucocorticoid receptor function by hypoxia(2022)
Authors: Tineke Vanderhaeghen, Steven Timmermans, Deepika Watts, Ville Paakinaho, Melanie Eggermont, Jolien Vandewalle, Charlotte Wallaeys, Lise Van Wyngene, Kelly Van Looveren, Louise Nuyttens, et al.
- MiR-511 deficiency protects mice from experimental colitis by reducing TLR3 and TLR4 responses via WD repeat and FYVE-domain-containing protein 1(2022)
Authors: Shafaque Rahman, Jolien Vandewalle, Patricia H. P. van Hamersveld, Caroline Verseijden, Olaf Welting, Aldo Jongejan, Pierina Casanova, Sybren L. Meijer, Claude Libert, Theodorus B. M. Hakvoort, et al.
Patents
1 - 1 of 1
- Means and methods to treat inflammation (Inventor)