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Researcher
Danny Huylebroeck
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → 30 Sep 2021 - Department of Human Genetics (Department)
Member
From1 Oct 2008 → 31 Dec 2011
Projects
1 - 10 of 19
- BMP signalling in endothelial function and dysfunctionFrom1 Oct 2019 → 30 Sep 2023Funding: BOF - projects
- Differential BMP signaling in endothelial cell 'fate' decision making processesFrom1 Oct 2016 → 30 Sep 2018Funding: BOF - Concerted Research Project from 1994
- p53 and its novel targets in healthy neurodevelopment and microcephaly, studied in mice.From1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Conditional knockout mice for the Smad-interacting protein and new DNA repair enzyme Tdp2: do embryonic neurogenesis defects contribute to adult neurodegeneration?From1 Jan 2014 → 31 Dec 2017Funding: FWO research project
- Modeling neurodevelopmental epilepsy syndromes: the example of mosaic deletion of PCDH19 and its influence on tangential migration of interneurons.From1 Jan 2014 → 31 Dec 2014Funding: FWO research grant KAN
- Shared mechanisms causing Mowat-Wilson syndrome and Pitt-Hopkins syndrome: analysis of Sip1 and Tcf4 function in brain development, from patient to mouse to patient.From1 Oct 2013 → 30 Sep 2014Funding: BOF - Other initiatives
- Development of mouse mutant resources for functional analyses of human diseases - Enhancing the translation of research into innovation.From1 Jan 2013 → 31 Dec 2016Funding: Research infrastructures
- New role for versatile BMP interpretation: regulation of endothelial cell heterogeneity in the mouseFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- Paracrine and transcriptional control of cell differentiation in organ development and repair.From1 Apr 2012 → 31 Dec 2017Funding: IUAP-VII, BOF - Doctoral projects
- Developmental origin of multiple defects of the nervous systems in Mowat-Wilson syndrome and its new insights for normal embryonic and adult neurogenesis.From1 Jan 2011 → 31 Dec 2013Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 98
- Type-2 CD8+ T-cell formation relies on interleukin-33 and is linked to asthma exacerbations(2023)
Authors: Danny Huylebroeck
- Local delivery of hrBMP4 as an anticancer therapy in patients with recurrent glioblastoma: a first-in-human phase 1 dose escalation trial(2023)
Authors: Danny Huylebroeck
- 3D chromatin reprogramming primes human memory TH2 cells for rapid recall and pathogenic dysfunction(2023)
Authors: Danny Huylebroeck
- Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson Syndrome(2023)
Authors: Danny Huylebroeck
- Efficient generation of ETX embryoids that recapitulate the entire window of murine egg cylinder development(2023)
Authors: An Zwijsen, Danny Huylebroeck
- Comparative single-cell RNA-sequencing profiling of BMP4-treated primary glioma cultures reveals therapeutic markers(2022)
Authors: Panagiotis Karras, Chris Marine, Danny Huylebroeck
Pages: 2133 - 2145 - Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity(2021)
Authors: Danny Huylebroeck
- ZEB2, the Mowat-Wilson Syndrome Transcription Factor: Confirmations, Novel Functions, and Continuing Surprises(2021)
Authors: Danny Huylebroeck
- Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis(2021)
Authors: Willeke de Haan, Wouter Dheedene, Baki Topal, An Zwijsen, Danny Huylebroeck, Aernout Luttun
Pages: 1262 - 1275 - Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner(2021)
Authors: Danny Huylebroeck