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Researcher
Danny Huylebroeck
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → 30 Sep 2021 - Department of Human Genetics (Department)
Member
From1 Oct 2008 → 31 Dec 2011
Projects
1 - 10 of 19
- BMP signalling in endothelial function and dysfunctionFrom1 Oct 2019 → 30 Sep 2023Funding: BOF - projects
- Differential BMP signaling in endothelial cell 'fate' decision making processesFrom1 Oct 2016 → 30 Sep 2018Funding: BOF - Concerted Research Project from 1994
- p53 and its novel targets in healthy neurodevelopment and microcephaly, studied in mice.From1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Conditional knockout mice for the Smad-interacting protein and new DNA repair enzyme Tdp2: do embryonic neurogenesis defects contribute to adult neurodegeneration?From1 Jan 2014 → 31 Dec 2017Funding: FWO research project
- Modeling neurodevelopmental epilepsy syndromes: the example of mosaic deletion of PCDH19 and its influence on tangential migration of interneurons.From1 Jan 2014 → 31 Dec 2014Funding: FWO research grant KAN
- Shared mechanisms causing Mowat-Wilson syndrome and Pitt-Hopkins syndrome: analysis of Sip1 and Tcf4 function in brain development, from patient to mouse to patient.From1 Oct 2013 → 30 Sep 2014Funding: BOF - Other initiatives
- Development of mouse mutant resources for functional analyses of human diseases - Enhancing the translation of research into innovation.From1 Jan 2013 → 31 Dec 2016Funding: Research infrastructures
- New role for versatile BMP interpretation: regulation of endothelial cell heterogeneity in the mouseFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- Paracrine and transcriptional control of cell differentiation in organ development and repair.From1 Apr 2012 → 31 Dec 2017Funding: IUAP-VII, BOF - Doctoral projects
- Developmental origin of multiple defects of the nervous systems in Mowat-Wilson syndrome and its new insights for normal embryonic and adult neurogenesis.From1 Jan 2011 → 31 Dec 2013Funding: Foundations, funds and other with scientific goal
Publications
41 - 50 of 98
- Zeb2 recruits HDAC-NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination(2016)
Authors: An Zwijsen, Danny Huylebroeck
Pages: 1060 - + - Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals(2016)
Authors: Danny Huylebroeck
Pages: 2829 - 2841 - The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2(2016)
Authors: Danny Huylebroeck
Pages: 897 - 911 - The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways(2016)
Authors: An Zwijsen, Danny Huylebroeck
Pages: 303 - 13 - BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells(2016)
Authors: Ruben Dries, Vanesa Abon Escalona, Danny Huylebroeck, An Zwijsen
Pages: 85 - 94 - Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection(2015)
Authors: Eve Seuntjens, Danny Huylebroeck
Pages: 2015 - 25 - Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection(2015)
Authors: Eve Seuntjens, Agata Stryjewska, Danny Huylebroeck
Pages: 2027 - 39 - Smad1/5/8 are myogenic regulators of murine and human mesoangioblasts(2015)
Authors: Domiziana Costamagna, Mattia Quattrocelli, Lieve Umans, An Zwijsen, Danny Huylebroeck, Maurilio Sampaolesi
Pages: 73 - 87 - ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling(2015)
Authors: Danny Huylebroeck
Pages: 5794 - INFRAFRONTIER--providing mutant mouse resources as research tools for the international scientific community(2015)
Authors: Danny Huylebroeck
Pages: D1171 - D1175