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Researcher
Danny Huylebroeck
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → 30 Sep 2021 - Department of Human Genetics (Department)
Member
From1 Oct 2008 → 31 Dec 2011
Projects
11 - 19 of 19
- An esiRNA-based approach to study reciprocal transcriptional regulation of TGFbeta family signaling components in ES cell identity and neural conversion.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project
- Multiple Sip1/Zfhx1b knockout mouse models explaining clinical signs of Mowat-Wilson Syndrome.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- InfraMouseFrom29 Oct 2010 → 30 Oct 2015Funding: Hercules - Large scale research infrastructure
- Investigation of the role of Sip1 in BMP-controlled aldult neurogenesis in the mouse central nervous system in baseline conditions and upon stroke.From1 Oct 2010 → 15 Oct 2017Funding: IWT personal funding - strategic basic research grants
- Growth factor signal interpretation in stem cells and the early embryo.From1 Oct 2010 → 30 Sep 2015Funding: BOF - Concerted Research Project from 1994
- Characterization of signaling pathways involved in differenttiation of pluripotent stem cells towards liver cellsFrom1 Aug 2010 → 31 Jul 2014Funding: Own budget, for example: patrimony, inscription fees, gifts
- Paracrine and transcriptional regulation of renewal and differentiation of embryonic and adult multi-potent progenitor cells in vertebratesFrom1 Oct 2009 → 30 Sep 2014Funding: BOF - Other initiatives
- A multi-parametric esiRNA screen addressing reciprocal signalling in ES cell identity and neural conversionFrom1 Oct 2009 → 4 Jan 2017Funding: IWT personal funding - strategic basic research grants
- The role of the transciption factor ZIC2 in Canonical Wnt signalling.From1 Sep 2008 → 15 Nov 2016Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 98
- Type-2 CD8+ T-cell formation relies on interleukin-33 and is linked to asthma exacerbations(2023)
Authors: Danny Huylebroeck
- Local delivery of hrBMP4 as an anticancer therapy in patients with recurrent glioblastoma: a first-in-human phase 1 dose escalation trial(2023)
Authors: Danny Huylebroeck
- 3D chromatin reprogramming primes human memory TH2 cells for rapid recall and pathogenic dysfunction(2023)
Authors: Danny Huylebroeck
- Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson Syndrome(2023)
Authors: Danny Huylebroeck
- Efficient generation of ETX embryoids that recapitulate the entire window of murine egg cylinder development(2023)
Authors: An Zwijsen, Danny Huylebroeck
- Comparative single-cell RNA-sequencing profiling of BMP4-treated primary glioma cultures reveals therapeutic markers(2022)
Authors: Panagiotis Karras, Chris Marine, Danny Huylebroeck
Pages: 2133 - 2145 - Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity(2021)
Authors: Danny Huylebroeck
- ZEB2, the Mowat-Wilson Syndrome Transcription Factor: Confirmations, Novel Functions, and Continuing Surprises(2021)
Authors: Danny Huylebroeck
- Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis(2021)
Authors: Willeke de Haan, Wouter Dheedene, Baki Topal, An Zwijsen, Danny Huylebroeck, Aernout Luttun
Pages: 1262 - 1275 - Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner(2021)
Authors: Danny Huylebroeck