Researcher
Delfien Syx
- Disciplines:Paediatrics and neonatology, Palliative care and end-of-life care, Laboratory medicine, Other translational sciences, Molecular and cell biology, Regenerative medicine, Nursing, Other clinical sciences, Other basic sciences, Other paramedical sciences, Other health sciences, Other medical and health sciences, Systems biology, Genetics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Sep 2008 → 30 Sep 2018
Projects
1 - 5 of 5
- Zebrafish as a model to study pain in Ehlers-Danlos syndromesFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Understanding human linkeropathies: study of the phenotypic and molecular consequences of defective biosynthesis of the glycosaminoglycan tetrasaccharide linker region.From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- An integrated translational platform to improve the management and outcome of rare heritable connective tissue diseaseFrom1 Jan 2021 → TodayFunding: BOF - projects
- Identifying a pain signature in classical Ehlers-Danlos syndromeFrom1 Nov 2020 → 30 Sep 2023Funding: FWO fellowships
- Study of mediators and pathways contributing to chronic pain in Ehlers-Danlos syndrome From1 Oct 2016 → 30 Sep 2019Funding: BOF - Other initiatives
Publications
11 - 19 of 19
- Hypomorphic zebrafish models mimic the musculoskeletal phenotype of β4GalT7-deficient Ehlers-Danlos syndrome(2020)
Authors: Sarah Delbaere, Tim Van Damme, Delfien Syx, Sofie Symoens, Paul Coucke, Andy Willaert, Fransiska Malfait
Pages: 59 - 75 - b3galt6 Knock-out zebrafish recapitulate β3GalT6-deficiency disorders in human and reveal a trisaccharide proteoglycan linkage region(2020)
Authors: Sarah Delbaere, Adelbert De Clercq, Shuji Mizumoto, Fredrik Noborn, Jan Willem Bek, Charlotte Gistelinck, Delfien Syx, Phil L. Salmon, Paul Coucke, Göran Larson, et al.
- The clinical and mutational spectrum of B3GAT3 linkeropathy : two case reports and literature review(2019)
Authors: Marlies Colman, Tim Van Damme, Elisabeth Steichen-Gersdorf, Franco Laccone, Sheela Nampoothiri, Delfien Syx, Brecht Guillemyn, Sofie Symoens, Fransiska Malfait
- Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β(2019)
Authors: Juan Li, Marco Ritelli, Cindy S Ma, Geetha Rao, Tanwir Habib, Emilie Corvilain, Salim Bougarn, Sophie Cypowyj, Lucie Grodecká, Romain Lévy, et al.
- Peripheral mechanisms contributing to osteoarthritis pain(2018)
Authors: Delfien Syx, Phuong B. Tran, Rachel E. Miller, Anne-Marie Malfait
- Knockdown and knockout zebrafish models for the β4GalT7-deficient type of Ehlers-Danlos syndrome reveal distinctive and overlapping phenotypic features(2018)
Authors: Sarah Delbaere, Tim Van Damme, Delfien Syx, Sofie Symoens, Andy Willaert, Fransiska Malfait
Number of pages: 1 - Novel translational discovery study of genes and SNPS associated with osteoarthritis pain(2017)Volume: 25
Authors: R. E. Miller, Delfien Syx, S. Ishihara, R. J. Miller, A. M. Valdes, A. -M. Malfait
Pages: S36 - S36 - Zebrafish modeling of the β4GalT7-deficient type of Ehlers-Danlos syndrome(2017)
Authors: Sarah Delbaere, Tim Van Damme, Paul Coucke, Sofie Symoens, Delfien Syx, Andy Willaert, Fransiska Malfait
Number of pages: 1 - Microarray analyses of dorsal root ganglia for the study of pathways contributing to pain in experimental osteoarthritis(2016)Volume: 68
Authors: Rachel E. Miller, Shingo Ishihara, Delfien Syx, Richard J. Miller, Ana M. Valdes, Anne-Marie Malfait
Number of pages: 1