Researcher
Diether Lambrechts
- Disciplines:Morphological sciences, Oncology
Affiliations
- Laboratory of Translational Genetics (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2017 → Today - Laboratory of Translational Genetics (VIB-KU Leuven) (Division)
Member
From1 Jan 2012 → Today
Projects
1 - 10 of 63
- A single-cell approach to identify biomarkers of efficacy and toxicity for immune checkpoint blockade combinations in non-small cell lung cancerFrom5 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Multiomic Integration of cell-free DNA profiles to Advance Disease OutcomeFrom1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Connecting Single-cell Immune Profiling in Peripheral Blood with Intratumoral T Cell Expansion in Breast Cancer Upon Checkpoint ImmunotherapyFrom24 Aug 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Developing personalized treatment for advanced penile cancer trough establishment of Patient-Derived Tumor Xenografts (PDTXs).From9 Aug 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Alternative RNA splicing as a predictor of response to checkpoint immunotherapyFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Single-cell omics data analysis in translational oncologyFrom1 Feb 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- EU-Genomics: EU Infrastructure for Genome AnalysisFrom1 Jan 2021 → TodayFunding: FWO Large scale research infrastructure
- Epigenetic and Spatial Single-cell profiling in the context of Cancer ImmunotherapyFrom1 Jan 2021 → TodayFunding: FWO research project
- Defining (epi)genomic transition from precursor lesion to invasive rare ovarian cancerDefining (epi)genomic transition from precursor lesion to invasive rare ovarian cancerFrom1 Apr 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- T Cell Expansion and Tumour Neoantigen Evolution during Checkpoint ImmunotherapyFrom1 Jan 2020 → TodayFunding: FWO research project
Publications
1 - 10 of 514
- Molecular Heterogeneity Between Paired Primary and Metastatic Lesions from Clear Cell Renal Cell Carcinoma.(2022)
Authors: Eduard Roussel, Lisa Kinget, Diether Lambrechts
Pages: 54 - 57 - PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.(2022)
Authors: Margherita Demicco, Ginevra Doglioni, Anke Vandekeere, Juan Fernandez Garcia, David Nittner, Francesca Rizzollo, Panagiotis Karras, Dorien Broekaert, Sofie Demeyer, Ayse Bassez, et al.
Pages: 747 - 753 - Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancer(2022)
Authors: An Coosemans, Toon Van Gorp, Tom Venken, Ruben Heremans, Thomas Holland Bourne, Ben Van Calster, Diether Lambrechts
Number of pages: 9 - Determinants of 25-hydroxyvitamin D Status in a Cutaneous Melanoma Population.(2022)
Authors: Julie De Smedt, Laudine Janssen, Dirk Vanderschueren, Kris Bogaerts, Oliver Bechter, Jaak Billen, Diether Lambrechts, Maria Garmyn
Pages: adv00692 - Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer(2022)
Authors: Lisa Moris, Diether Lambrechts, Christine Helsen, Bart Ghesquière, Stefaan Soenen, Roy Eerlings, Sarah El Kharraz, Hendrik Van Poppel, Steven Joniau, Frank Claessens
Pages: 527 - 541Number of pages: 15 - Randomized CLIO/BGOG-ov10 trial of olaparib monotherapy versus physician's choice chemotherapy in relapsed ovarian cancer.(2022)
Authors: Els Van Nieuwenhuysen, Sileny Han, Siel Olbrecht, Patrick Neven, Diether Lambrechts, Toon Van Gorp, Ignace Vergote
Pages: 14 - 22 - CA-125 Levels Are Predictive of Survival in Low-Grade Serous Ovarian Cancer-A Multicenter Analysis(2022)
Authors: Diether Lambrechts
Number of pages: 12 - European experts consensus: BRCA/homologous recombination deficiency testing in first-line ovarian cancer(2022)
Authors: Ignace Vergote, Diether Lambrechts
Pages: 276 - 287Number of pages: 12 - Organoids from human tooth showing epithelial stemness phenotype and differentiation potential(2022)
Authors: Lara Hemeryck, Florian Hermans, Diether Lambrechts, Hugo Vankelecom
Number of pages: 23 - c-MET/VEGFR-2 co-localisation impacts on survival following bevacizumab therapy in epithelial ovarian cancer: an exploratory biomarker study of the phase 3 ICON7 trial(2022)
Authors: Diether Lambrechts
Number of pages: 11