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Researcher
Dietmar Thal
- Disciplines:Anatomical pathology, Neurological and neuromuscular diseases
Affiliations
- Laboratory for Neuropathology (Lab)
Responsible
From1 May 2019 → Today - Translational Cell & Tissue Research (Division)
Member
From1 May 2019 → Today - Laboratory for Neuropathology (Lab)
Member
From1 Apr 2016 → 30 Apr 2019 - Department of Neurosciences (Department)
Member
From1 Oct 2015 → 31 Mar 2016
Projects
1 - 10 of 23
- Necroptosis and pyroptosis pathway inhibition in mouse models of Alzheimer's disease pathology: Can we protect neurons from dying?From1 Jan 2024 → TodayFunding: Private funding of national origin - undefined
- Cell death and neuron degeneration in Amyotrophic Lateral Sclerosis (ALS)From3 Nov 2022 → 15 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Mechanisms of motor neuron degeneration in amyotrophic lateral sclerosis (ALS): cell death pathways and/or aberrant communication between cell body and neuromuscular junctionsFrom1 Oct 2022 → TodayFunding: BOF - projects
- Selective vulnerability in Alzheimer’s disease and frontotemporal degeneration: integration of postmortem MRI, mass-spectrometry and histopathologyFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
- Risk factors for Alzheimer’s diseaseFrom21 Jun 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Aβ and tau pathology in the retina of Alzheimer’s disease patients and non-demented elderly individuals and its relation to the brain pathologyFrom1 Mar 2021 → TodayFunding: BOF - doctoral mandates
- Investigating the role of tau aggregates in neurodegenerationFrom15 Feb 2021 → TodayFunding: FWO fellowships
- Risk factors for neuropathological hallmark lesions and cell death in preclinical and symptomatic Alzheimer’s disease: a chance for age-of-onset prediction?From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Deciphering Tau structure and oligomerization propensities: Towards innovative therapeutics, prognostics and diagnosticsFrom1 Jan 2021 → 31 Dec 2023Funding: IOF - technology validation in lab
Publications
21 - 30 of 126
- LATE-NC staging in routine neuropathologic diagnosis: an update(2023)
Authors: Dietmar Thal
- Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies(2023)
Authors: Dietmar Thal
- Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons(2023)
Authors: Marta Koper, Evelien Van Schoor, Jolien Schaeverbeke, Rik Vandenberghe, Thomas Tousseyn, Bart De Strooper, Dietmar Thal
Pages: 175 - 195 - Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies (Dec, 10.1007/s00401-022-02525-1, 2022)(2023)
Authors: Dietmar Thal
Pages: 263 - 263 - Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics(2023)
Authors: Dietmar Thal, Klara Gawor
- Unravelling the mechanisms of motor neuron degeneration in relation to TDP-43 pathology in amyotrophic lateral sclerosis(2022)
Authors: Evelien Van Schoor, Dietmar Thal, Ludo Van Den Bosch, Philip Van Damme
- Anatomical barriers against SARS-CoV-2 neuroinvasion at vulnerable interfaces visualized in deceased COVID-19 patients(2022)
Authors: Marnick Clijsters, Wout Backaert, Dirk Jochmans, Lies Laenen, Yves Debaveye, Paul De Munter, Jan Gunst, Mark Jorissen, Katrien Lagrou, Johan Neyts, et al.
Pages: 3919 - + - GVD-necroptosis as a driving process of neurodegeneration in Alzheimer’s disease(2022)
Authors: Marta Koper, Dietmar Thal, Bart De Strooper
- The central role of tau in Alzheimer’s disease: From neurofibrillary tangle maturation to the induction of cell death(2022)
Authors: Dietmar Thal, Sandra Oliveira Tomé
Pages: 204 - 217 - Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer's disease(2022)
Authors: Tessa Robberechts, Marta Koper, Joost Schymkowitz, Frederic Rousseau, Dietmar Thal
Pages: 3558 - 3570