Researcher
Dietmar Thal
- Disciplines:Anatomical pathology, Neurological and neuromuscular diseases
Affiliations
- Laboratory for Neuropathology (Lab)
Responsible
From1 May 2019 → Today - Translational Cell & Tissue Research (Division)
Member
From1 May 2019 → Today - Laboratory for Neuropathology (Lab)
Member
From1 Apr 2016 → 30 Apr 2019 - Department of Neurosciences (Department)
Member
From1 Oct 2015 → 31 Mar 2016
Projects
1 - 10 of 23
- Necroptosis and pyroptosis pathway inhibition in mouse models of Alzheimer's disease pathology: Can we protect neurons from dying?From1 Jan 2024 → TodayFunding: Private funding of national origin - undefined
- Cell death and neuron degeneration in Amyotrophic Lateral Sclerosis (ALS)From3 Nov 2022 → 15 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Mechanisms of motor neuron degeneration in amyotrophic lateral sclerosis (ALS): cell death pathways and/or aberrant communication between cell body and neuromuscular junctionsFrom1 Oct 2022 → TodayFunding: BOF - projects
- Selective vulnerability in Alzheimer’s disease and frontotemporal degeneration: integration of postmortem MRI, mass-spectrometry and histopathologyFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
- Risk factors for Alzheimer’s diseaseFrom21 Jun 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Aβ and tau pathology in the retina of Alzheimer’s disease patients and non-demented elderly individuals and its relation to the brain pathologyFrom1 Mar 2021 → TodayFunding: BOF - doctoral mandates
- Investigating the role of tau aggregates in neurodegenerationFrom15 Feb 2021 → TodayFunding: FWO fellowships
- Risk factors for neuropathological hallmark lesions and cell death in preclinical and symptomatic Alzheimer’s disease: a chance for age-of-onset prediction?From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Deciphering Tau structure and oligomerization propensities: Towards innovative therapeutics, prognostics and diagnosticsFrom1 Jan 2021 → 31 Dec 2023Funding: IOF - technology validation in lab
Publications
41 - 50 of 127
- Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers(2022)
Authors: Nikolaos Louros, Emiel Michiels, Katerina Konstantoulea, Dietmar Thal, Frederic Rousseau, Joost Schymkowitz
- Frontotemporal Lobar Degeneration Case with an N-Terminal TUBA4A Mutation Exhibits Reduced TUBA4A Levels in the Brain and TDP-43 Pathology(2022)
Authors: Evelien Van Schoor, Mathieu Vandenbulcke, Valérie Bercier, Rik Vandenberghe, Philip Van Damme, Ludo Van Den Bosch, Dietmar Thal
- Large- and Small-Fiber Neuropathy in Patients with Tarlov Cysts(2022)
Authors: Mieke Hulens, Dietmar Thal, Chris Bervoets, Wim Dankaerts
Pages: 193 - 202 - The probabilistic model of Alzheimer disease: the amyloid hypothesis revised(2022)
Authors: Dietmar Thal
Pages: 53 - 66 - Demenz Naturwissenschaftliche, rechtliche und ethische Aspekte(2022)
Authors: Dietmar Thal
Number of pages: 174 - Article Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb(2021)
Authors: Marnick Clijsters, Wout Backaert, Arno Vanstapel, Lukas Marcelis, Hai Zhou, Yves Debaveye, Paul De Munter, Jan Gunst, Mark Jorissen, Katrien Lagrou, et al.
Pages: 5932 - + - TDP-43: A key player in Alzheimer's Disease(2021)
Authors: Sandra Oliveira Tomé, Dietmar Thal, Rik Vandenberghe
- Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease(2021)
Authors: Hannah Walgrave, Sriram Balusu, Nicky Thrupp, Rudi D'Hooge, Dietmar Thal, Mark Fiers, Bart De Strooper
Pages: 1805 - + - Tau Pathology Associated With Parkinsonism and Mutation of Mitochondrial DNA Helicase Gene TWNK(2021)
Authors: Wim Vandenberghe, Dorien Imberechts, Koen Van Laere, Gert De Hertogh, Dietmar Thal
- Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques(2021)
Authors: Pranav Preman, Sebastian Munck, Dietmar Thal, Bart De Strooper