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Researcher
Dirk Daelemans
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Department of Microbiology, Immunology and Transplantation (Department)
Member
From1 Oct 2013 → 31 Oct 2013 - Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 2000 → Today
Projects
11 - 20 of 29
- Identification and development of novel therapeutic options to treat primary diagnosed and recurrent glioblastomaFrom1 Sep 2019 → 1 Sep 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of a novel class of Exportin 1 (XPO1/CRM1) inhibitors for anti-cancer therapyFrom21 Aug 2019 → 15 Dec 2023Funding: BOF - doctoral mandates
- The study and application of CRISPR-Cas systemsFrom1 Jul 2019 → 16 Mar 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Unravelling the mechanisms of drug resistance to proteasome inhibitors to optimize treatment in patients with multiple myeloma.From1 Jul 2019 → 30 Jun 2023Funding: Foundations, funds and other with scientific goal
- Unravelling the mechanisms of drug resistance to proteasome inhibitors to optimize treatment in patients with multiple myelomaFrom10 Sep 2018 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant
- GENERATION OF ARTIFICIAL NUCLEIC ACID SYSTEMS FOR BIOTECHNOLOGY AND THERAPEUTICSFrom1 Oct 2017 → 17 Jun 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Systematic identification of regulators of the XPO1-mediated nuclear exportFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Role of nucleocytoplasmic transport in amyotrophic lateral scleroris (ALS)From1 Oct 2016 → 25 Mar 2021Funding: FWO fellowships
- Automated real-time quantitative live cell analysisFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- Exploration of nuclear import as novel anticancer targetFrom1 Sep 2016 → 28 Feb 2018Funding: BOF - Doctoral projects
Publications
1 - 10 of 156
- Novel acrylonitrile derived imidazo[4,5-b]pyridines as antioxidants and potent antiproliferative agents for pancreatic adenocarcinoma.(2024)
Authors: Dirk Daelemans
Pages: 131239 - Synthesis and Biological Evaluation of Novel Amino and Amido Substituted Pentacyclic Benzimidazole Derivatives as Antiproliferative Agents(2024)
Authors: Dirk Daelemans
- New sugar-incorporated N-heterocyclic carbene precursors and their Ag(I) and Pd(II) complexes: Synthesis, characterization, and cytotoxicity studies(2024)
Authors: Dirk Daelemans, Wim Dehaen, Luc Van Meervelt
- Development of a novel class of Exportin 1 (XPO1/CRM1) inhibitors for anti-cancer therapy(2023)
Authors: Felien Reniers, Wim Dehaen, Dirk Daelemans
- 4-Octyl itaconate reduces influenza A replication by targeting the nuclear export protein CRM1(2023)
Authors: Dirk Daelemans
- Synthesis and Antiproliferative Activity of 2,6-Disubstituted Imidazo[4,5-b]pyridines Prepared by Suzuki Cross Coupling(2023)
Authors: Dirk Daelemans
- Polyketide Synthase-Mediated O-Methyloxime Formation in the Biosynthesis of the Oximidine Anticancer Agents(2023)
Authors: Eveline Vriens, Dries De Ruysscher, Sofie Dekimpe, Gert Steurs, Ahmed Shemy, Dirk Daelemans, Wim De Borggraeve, Eveline Lescrinier, Joleen Masschelein
- TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry(2023)
Authors: Jim Baggen, Maarten Jacquemyn, Els Vanstreels, Hendrik Jan Thibaut, Piet Maes, Dirk Daelemans
Pages: 3427 - + - Novel hydroxy- and amidino-substituted benzimidazoles and benzothiazoles as antibacterial and antiproliferative agents(2023)
Authors: Dirk Daelemans
Pages: 1251 - 1272 - Biological evaluation of novel amidino substituted coumarin-benzazole hybrids as promising therapeutic agents(2023)
Authors: Dirk Daelemans
Pages: 957 - 968