Researcher
Fransiska Malfait
- Keywords:collagen, OSteogenesis Imperfecta, pain, connective tissue, proteoglycans, heritavle connective tissue disorders, Genetics, Ehlers-Danlos Syndromes
- Disciplines:Medical genomics, Musculo-skeletal systems
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2000 → 30 Sep 2018
Projects
1 - 10 of 20
- Zebrafish as a model to study pain in Ehlers-Danlos syndromesFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Ehlers-Danlos Grant Agreement Fransiska Malfait: "Elucidating the genetic basis of Ehlers-Danlos syndromes using whole genome sequencing"From1 Dec 2022 → TodayFunding: Foreign public sponsor
- Ehlers-Danlos Grant Agreement Delfien Syx: "Generation of zebrafish models of classical Ehlers-Danlos syndrome"From1 Dec 2022 → TodayFunding: Foreign public sponsor
- Understanding human linkeropathies: study of the phenotypic and molecular consequences of defective biosynthesis of the glycosaminoglycan tetrasaccharide linker region.From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Investigating Pain-Related Phenotypes in a Mouse Model of Ehlers-Danlos SyndromesFrom16 Aug 2021 → TodayFunding: Other international institutions, not mentioned elsewhere
- Unraveling the Pathomechanisms Underlying Hypermobile Ehlers-Danlos Syndrome: an Integrated Omics ApproachFrom16 Aug 2021 → TodayFunding: Other international institutions, not mentioned elsewhere
- An integrated translational platform to improve the management and outcome of rare heritable connective tissue diseaseFrom1 Jan 2021 → TodayFunding: BOF - projects
- Research equipment for behavior analysis in zebrafish disease models.From1 Dec 2020 → 30 Nov 2022Funding: BOF - scientific equipment program
- Identifying a pain signature in classical Ehlers-Danlos syndromeFrom1 Nov 2020 → 30 Sep 2023Funding: FWO fellowships
- Zebrafish as a model to study pain in rare subtypes of Ehlers-Danlos syndromesFrom1 Nov 2020 → 31 Dec 2021Funding: Other international institutions, not mentioned elsewhere
Publications
31 - 40 of 204
- Animal models of Ehlers–Danlos syndromes : phenotype, pathogenesis, and translational potential(2021)
Authors: Robin Vroman, Anne-Marie Malfait, Rachel Miller, Fransiska Malfait, Delfien Syx
- Pain in the Ehlers–Danlos syndromes : mechanisms, models, and challenges(2021)
Authors: Fransiska Malfait, Marlies Colman, Robin Vroman, Inge De Wandele, Lies Rombaut, Rachel E. Miller, Anne-Marie Malfait
Pages: 429 - 445 - Does muscle strength change over time in patients with hypermobile Ehlers-Danlos syndrome/ Hypermobility Spectrum Disorder? An 8-year follow-up study(2021)
Authors: Marie Coussens, Bruno Lapauw, Bert Celie, Thiberiu Banica, Inge De Wandele, V Pacey, Fransiska Malfait, Lies Rombaut
Pages: 1041 - 1048 - Patient perspectives on employment participation in the 'hypermobile Ehlers-Danlos syndrome'(2021)
Authors: Stijn De Baets, Liesbeth Verhoost, Inge De Wandele, Fransiska Malfait, Dominique Van de Velde
Pages: 668 - 677 - Heritable connective tissue disorders in childhood : increased fatigue, pain, disability and decreased general health(2021)
Authors: Jessica Warnink-Kavelaars, Lisanne E. de Koning, Lies Rombaut, Mattijs W. Alsem, Leonie A. Menke, Jaap Oosterlaan, I Buizer, Annemieke, Raoul H. H. Engelbert, Marieke J. H. Baars, Rosa de Boer, et al.
- The impact of COVID-19 on rare and complex connective tissue diseases : the experience of ERN ReCONNET(2021)
Authors: Rosaria Talarico, Silvia Aguilera, Tobias Alexander, Zahir Amoura, Ana M. Antunes, Laurent Arnaud, Tadej Avcin, Lorenzo Beretta, Stefano Bombardieri, Gerd R. Burmester, et al.
Pages: 177 - 184 - Muscle activity and scapular kinematics in individuals with multidirectional shoulder instability : a systematic review(2021)
Authors: Valentien Spanhove, Matthias Van Daele, Aäron Van den Abeele, Lies Rombaut, Birgit Castelein, Fransiska Malfait, Inge De Wandele
- More than meets the eye : expanding and reviewing the clinical and mutational spectrum of brittle cornea syndrome(2021)
Authors: Tibbe Dhooge, Tim Van Damme, Sheela Nampoothiri, Anil Radhakrishnan, Pelin O. Simsek-Kiper, Gulen E. Utine, Maryse Bonduelle, Isabelle Migeotte, Osama Essawi, Serdar Ceylaner, et al.
Pages: 711 - 730 - Biallelic variants in MESD, which encodes a WNT-signaling-related protein, in four new families with recessively inherited osteogenesis imperfecta(2021)
Authors: Thao T. Tran, Rachel B. Keller, Brecht Guillemyn, Melanie Pepin, Jane E. Corteville, Samir Khatib, Mohammad-Sadegh Fallah, Sirous Zeinali, Fransiska Malfait, Peter Witters, et al.
- Hypomorphic zebrafish models mimic the musculoskeletal phenotype of β4GalT7-deficient Ehlers-Danlos syndrome(2020)
Authors: Sarah Delbaere, Tim Van Damme, Delfien Syx, Sofie Symoens, Paul Coucke, Andy Willaert, Fransiska Malfait
Pages: 59 - 75