Researcher
Frauke Coppieters
- Keywords:inherited blindness, non-coding RNA, gene therapy
- Disciplines:Ophthalmology, Genetics, Molecular medicine, Clinical genetics and molecular diagnostics, Stem cell biology, Medical transcriptomics, Nucleic acids, Molecular diagnostics, Medical genomics
Affiliations
- Department of Pharmaceutics (Department)
Member
From21 Sep 2020 → Today - Department of Biomolecular Medicine (Department)
Member
From1 Oct 2019 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Nov 2005 → 13 Jan 2018
Projects
1 - 10 of 12
- The role of upstream open reading frames (uORFs) in retinal health, disease and therapyFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Design of a novel antisense oligonucleotide therapy for inherited blindnessFrom15 Oct 2023 → TodayFunding: IOF - technology validation in lab
- Design of a novel antisense oligonucleotide therapy for inherited retinal diseases - Year 3From1 Jul 2023 → TodayFunding: Other EU initiatives out of framework
- Incucyte S3: Comprehensive cellular phenotyping using high-throughput live cell imagingFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Functional study of a novel, long non-coding RNA (lncRNA) upstream of ABCA4 in retina and blindnessFrom1 Nov 2022 → TodayFunding: BOF - doctoral mandates
- Design of a novel antisense oligonucleotide therapy for inherited blindnessFrom1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Design of a novel antisense oligonucleotide therapy for inherited blindnessFrom1 Nov 2020 → 31 Oct 2021Funding: BOF - doctoral mandates
- Precision medicine in inherited blindness using integrated omics in human and animal modelsFrom1 Jan 2020 → TodayFunding: BOF - projects
- Antisense oligonucleotide therapy for genetic heterogeneous rare disordersFrom1 Nov 2019 → TodayFunding: BOF - projects
- Sequencing Expertise Centre (Life Sciences)From1 Feb 2017 → 30 Nov 2022Funding: BOF - Doctoral projects
Publications
1 - 10 of 23
- Differential protease content of mast cells and the processing of IL-33 in Alternaria alternata induced allergic airway inflammation in mice(2023)
Authors: Olga Krysko, Darya Korsakova, Andrea Renate Teufelberger, Amse De Meyer, Jill Steels, Natalie De Ruyck, Judith van Ovost, Sharon Van Nevel, Gabriële Holtappels, Frauke Coppieters, et al.
- Cost-effective sequence analysis of 113 genes in 1,192 probands with retinitis pigmentosa and Leber congenital amaurosis(2023)
Authors: Daan M. Panneman, Rebekkah J. Hitti-Malin, Lara K. Holtes, Suzanne E. de Bruijn, Janine Reurink, Erica G. M. Boonen, Muhammad Imran Khan, Manir Ali, Sten Andréasson, Sandro Banfi, et al.
- Joubert syndrome(2022)
Authors: Frauke Coppieters, Elise Héon, Monika K. Grudzinska Pechhacker, Graeme C.M. Black, Jane L. Ashworth, Panagiotis I. Sergouniotis
Pages: 274 - 276 - Cell death stage dictates the immunogenicity of ferroptotic cancer cells(2021)Volume: 206
Authors: Iuliia Efimova, Elena Catanzaro, Robin Demuynck, Louis Van der Meeren, Frauke Coppieters, Claus Bachert, Andre Skirtach, Olga Krysko, Dmitri Krysko
Number of pages: 1 - Longitudinal phenotypic study of late-onset retinal degeneration due to a founder variant c.562C > A p.(Pro188Thr) in the C1QTNF5 gene(2021)
Authors: Julie De Zaeytijd, Frauke Coppieters, Marieke De Bruyne, Jasper Van Royen, Dimitri Roels, Rani Six, Caroline Van Cauwenbergh, Elfride De Baere, Bart Leroy
Pages: 521 - 532 - Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity(2020)
Authors: Iuliia Efimova, Elena Catanzaro, Louis Van der Meeren, Victoria Turubanova, Hamida Hammad, Tatiana Mishchenko, Maria Vedunova, Carmela Fimognari, Claus Bachert, Frauke Coppieters, et al.
- PCR based target enrichment for variant confirmation, gene panels and multiplex PCR sample tracking in a whole exome sequencing workflow(2019)Volume: 27
Authors: Frauke Coppieters, Thalia Van Laethem, Matthias De Smet, Paul Coucke, Elfride De Baere, Kathleen Claes, Björn Menten, Jo Vandesompele, Steve Lefever
Pages: 1660 - 1661 - Antisense oligonucleotide-based downregulation of the G56R pathogenic variant causing NR2E3-associated autosomal dominant retinitis pigmentosa(2019)
Authors: Sarah Naessens, Laurien Ruysschaert, Steve Lefever, Frauke Coppieters, Elfride De Baere
- Biallelic loss-of-function variants in RAX2, encoding a homeobox-containing Rax transcription factor, cause autosomal recessive inherited retinal disease(2018)
Authors: Stijn Van de Sompele, Claire Smith, Marianthi Karali, Marta Corton, Kristof Van Schil, Frank Peelman, Timothy Cherry, Toon Rosseel, Hannah Verdin, Julien Derolez, et al.
Number of pages: 1 - Homozygosity mapping-guided exome sequencing in LCA patients of consanguineous origin reveals mutations in known genes and a novel candidate gene(2017)Volume: 58
Authors: Basamat Almoallem Mohammed H, Kristof Van Schil, Laila Jeddawi, Bart Leroy, Frauke Coppieters, Elfride De Baere
Pages: 1242 - 1242