Researcher
Frederik De Smet
- Disciplines:Macromolecular and materials chemistry, Laboratory medicine, Morphological sciences
Affiliations
- Translational Cell & Tissue Research (Division)
Member
From1 Oct 2016 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → 30 Sep 2016 - Centre for Molecular and Vascular Biology (Division)
Member
From15 Nov 2003 → 30 Sep 2005
Projects
1 - 10 of 47
- Virtual StainingFrom15 Jan 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The malignant Glioma immuno-oncology matchmaker: towards data-driven precision medicine using spatially resolved radio-multiomicsFrom1 Jan 2024 → TodayFunding: HORIZON.2.1 - Health
- Mapping epigenetic regulatory pathways that drive Glioblastoma plasticity at single-cell resolutionFrom13 Nov 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding the RNA regulatory interactome landscape of radiation response in glioblastomaFrom13 Oct 2023 → TodayFunding: SCK (Study Centre Nuclear Energy)
- PEGASuS - PEdiatric Glioma Architecture Single cell and Spatial mapping: in search for effectors of radioresistanceFrom1 Oct 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Mapping the therapeutic potential of AG5 and its effects on TME using a multi-omics approach in IDHwt GBM patient-derived models.From1 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- A platform for advanced single-cell pathological profiling of immune-brain interactionsFrom15 Jun 2023 → TodayFunding: BOF - various
- Immunotherapy for childhood, adolescent, and adult Glioblastoma: towards tumour-immune interactions driven precision medicine using spatially resolved radio-multiomics.From15 Jan 2023 → TodayFunding: BOF - various
- Targeting radiation-induced plasticity in Glioblastoma: from fundamental insights to tailored therapeutic opportunitiesFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Unique IsoPlexis technology for multiplexed single cell functional profilingFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
Publications
1 - 10 of 67
- Recent advancements in tumour microenvironment landscaping for target selection and response prediction in immune checkpoint therapies achieved through spatial protein multiplexing analysis.(2024)
Authors: Madhavi Dipak Andhari, Frederik De Smet, Francesca Bosisio
Pages: 207 - 237 - Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma(2023)
Authors: Lise Finotto, Frederik De Smet, Ilse Geudens
- Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma(2023)
Authors: Lise Finotto, Basiel Cole, Maxime Vanmechelen, Bram Boeckx, Diether Lambrechts, Ludo Van Den Bosch, Steven De Vleeschouwer, Frederik De Smet
- ESTABLISHING A CLINICALLY RELEVANT MOUSE MODEL OF MESENCHYMAL GLIOBLASTOMA FOR STUDYING TME TARGETING TREATMENTS.(2023)
Authors: Ingrid Arijs, Diether Lambrechts, Frederik De Smet
- Extended heterogeneity mapping of pediatric brain tumors(2023)
Authors: Julie Messiaen, Frederik De Smet, Sandra Jacobs
- The tumor micro-environment in pediatric glioma: friend or foe?(2023)
Authors: Sandra Jacobs, Frederik De Smet
- Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII plus innate immune cells in rejection(2023)
Authors: Yannick Van Herck, Frederik De Smet, Katrien De Vusser, Dirk Kuypers, Diether Lambrechts, Elisabet Van Loon, Thibaut Vaulet, Francesca Bosisio, Maarten Naesens
- ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma(2023)
Authors: Veerle Haemels, Frederik De Smet
Pages: 2651 - 2667 - Functional Precision Oncology: Next-generation treatment rationale for glioblastoma Mapping the drug response heterogeneity using single cell protein analysis(2023)
Authors: Dena Panovska, Frederik De Smet
- Spatially resolved intracellular delivery of molecules at single cell level on a microelectrode array(2023)
Authors: Bastien Duckert, Liesbet Lagae, Rik Gijsbers, Frederik De Smet
Number of pages: 124
Patents
1 - 5 of 5
- Means and methods for generating improved proteins (Inventor)
- Means and methods for generating improved proteins (Inventor)
- Extracellular allosteric inhibitor binding domain from a tyrosine kinase receptor (Inventor)
- Methods for screening inhibitors of tumor associated protein aggregation (Inventor)
- Methods for screening inhibitors of tumour associated protein aggregation. (Inventor)