Researcher
H Llewelyn Roderick
- Disciplines:Physiology, Cell growth and development, Cell signalling, Epigenetics, Intracellular compartments and transport
Affiliations
- Experimental Cardiology (Division)
Responsible
From1 Oct 2023 → Today - Experimental Cardiology (Division)
Member
From1 Oct 2014 → Today
Projects
11 - 20 of 22
- Subcellular Ca2+ signalling microdomains regulating cardiomyocyte growth and functionFrom8 Sep 2021 → 15 Feb 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Linking functional microarchitecture of the myocardial infarction borderzone to arrhythmogenesisFrom1 Jan 2021 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Subcellular Ca2+ signalling microdomains regulating cardiomyocyte growth and functionFrom1 Jan 2021 → TodayFunding: BOF - doctoral mandates
- Cardiac fibrosis and fibroblast phenotypes in heart failure: probing heterogeneity and pathways for reversibilityFrom22 Jan 2020 → 22 Jan 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- Methylation of histone H3 lysine 9 by the Euchromatic Histone Methyl Transferases (EHMT1/2) regulates cardiac myocyte growth and proliferative responsesFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- "Epigenetic regulation of cardiac myocyte proliferation/cell cycle – from single cells to organ function."From8 Jan 2018 → 8 Jan 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of H3K9 methylation by Euchromatic Histone Methyl Transferases (EHMT1/2) in controlling cardiac myocyte growth and proliferative responses during health and disease.From1 Oct 2017 → 30 Sep 2021Funding: Fund Recuperation Fiscal Exemption, BOF - Concerted Research Project from 1994
- Development of a technology platform for next-generation cytometryFrom1 Jul 2016 → 30 Jun 2020Funding: FWO Large scale research infrastructure
- Microdomein interacties tussen de intracellulaire Ca kanalen IP3R and RyR na myocard infarctFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Quantitative approach to assess function and apoptosis changes in the H9C2 cardiomyocyte cell line following differentiation and Doxorubicin exposureFrom1 Dec 2014 → 8 Aug 2019Funding: BOF - doctoral mandates, BOF - Doctoral projects
Publications
1 - 10 of 80
- Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development.(2023)
Authors: H Llewelyn Roderick
Pages: 100135 - The ryanodine receptor microdomain in cardiomyocytes(2023)
Authors: Eef Dries, Guillaume Gilbert, H Llewelyn Roderick, Karin Sipido
- Heterogeneity of Repolarization and Cell-Cell Variability of Cardiomyocyte Remodeling Within the Myocardial Infarction Border Zone Contribute to Arrhythmia Susceptibility.(2023)
Authors: Dylan Vermoortele, Guillaume Gilbert, Mohamad Youness, Bernard Thienpont, Rik Willems, H Llewelyn Roderick, Piet Claus, Karin Sipido
- InsP3R-RyR channel crosstalk augments sarcoplasmic reticulum Ca2+ release and arrhythmogenic activity in post-MI pig cardiomyocytes.(2023)
Authors: Joshua Jeen Tung Chung, Eef Dries, Piet Claus, Karin Sipido, H Llewelyn Roderick
Pages: 47 - 59 - Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments(2023)
Authors: H Llewelyn Roderick, Geert Bultynck, Karin Sipido
- DEG (differentially expressed gene) or not DEG that is the question: Should we compare between datasets or not?(2023)
Authors: H Llewelyn Roderick
- Reversal of Right Ventricular Remodeling After Correction of Pulmonary Regurgitation in Tetralogy of Fallot(2023)
Authors: Bjorn Cools, Katrien Vandendriessche, Joeri Van Puyvelde, Mohamad Youness, H Llewelyn Roderick, Marc Gewillig, Karin Sipido, Piet Claus, Filip Rega
Pages: 301 - 305 - IP3R activity increases propensity of RyR-mediated sparks by elevating dyadic [Ca2+].(2023)
Authors: Joshua Jeen Tung Chung, H Llewelyn Roderick
- Cardiomyocyte differentiation from human induced pluripotent stem cells is delayed following knockout of Bcl-2(2023)
Authors: Tim Vervliet, Robin Duelen, Rita La Rovere, H Llewelyn Roderick, Maurilio Sampaolesi
- InsP3R-RyR Ca2+ channel crosstalk facilitates arrhythmias in the failing human ventricle(2022)
Authors: Guillaume Gilbert, Eef Dries, Rosa Donate Puertas, Ashutosh Tomar, Tobie Martens, Pieter Vanden Berghe, Filip Rega, Karin Sipido, H Llewelyn Roderick