Researcher
Hilde Brems
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for Neurofibromatosis Research (Division)
Responsible
From15 Jul 2022 → Today - Laboratory for Neurofibromatosis Research (Division)
Member
From19 Oct 2009 → 30 Sep 2017 - Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 5 of 5
- Importance of SPRED1 in melanomaFrom9 Dec 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Importance of SPRED1 in melanomaFrom1 Oct 2015 → 27 Mar 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Periosteal cell therapy as a new treatment of pseudarthrosis in children with NF1.From21 Oct 2013 → 10 Dec 2019Funding: IWT personal funding - strategic basic research grants, BOF - Doctoral projects
- Pathogenesis of congenital tibial bowing and pseudarthrosis in neurofibromatosis type 1.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project
- NF1-like syndromes: identification of new genes and further characterization of Legius syndrome using the mouse model.From1 Oct 2011 → 30 Sep 2017Funding: FWO fellowships
Publications
1 - 10 of 67
- Identification of Codon 146 KRAS Variants in Isolated Epidermal Nevus and Multiple Lesions in Oculoectodermal Syndrome: Confirmation of the Phenotypic Continuum of Mosaic RASopathies(2022)
Authors: Hilde Brems
Number of pages: 10 - Comprehensive immunomolecular profiling of endometrial carcinoma: A tertiary retrospective study(2021)
Authors: Lien Spans, Hilde Brems, Annouschka Laenen, Ignace Vergote, Toon Van Gorp, Els Van Nieuwenhuysen, Sileny Han, Anne-Sophie Van Rompuy, Isabelle Vanden Bempt
Pages: 694 - 701Number of pages: 8 - Multitumor Case Series of Germline BRCA1, BRCA2 and CHEK2-Mutated Patients Responding Favorably on Immune Checkpoint Inhibitors.(2021)
Authors: Lisa Kinget, Oliver Bechter, Kevin Punie, Hilde Brems, Paul Clement, Eduard Roussel, Yannick Van Herck, Maarten Albersen, Marcella Baldewijns, Patrick Schöffski, et al.
Pages: 3227 - 3239 - An update on congenital melanocytic nevus syndrome: A case report and literature review(2021)
Authors: Francesca Maria Bosisio, Hilde Brems, Greet De Vlieger, Maria Garmyn, Heidi Segers, Katrien Jansen, Lieven Lagae
Pages: 1497 - 1503Number of pages: 7 - MEK inhibition ameliorates social behavior phenotypes in a Spred1 knockout mouse model for RASopathy disorders(2021)
Authors: Sarah Borrie, Zsuzsanna Callaerts-Végh, Rudi D'Hooge, Eric Legius, Hilde Brems
Number of pages: 19 - A Patient with neonatal cholestasis.(2021)
Authors: Kristl Claeys, Eric Legius, Hilde Brems, David Cassiman, Pieter Vermeersch, Elena Levtchenko
Pages: 31 - 33 - Comprehensive targeted next-generation sequencing approach in the molecular diagnosis of gastrointestinal stromal tumor(2020)
Authors: Isabelle Vanden Bempt, Raphael Sciot, Lien Spans, Hilde Brems, Baki Topal, Patrick Schöffski, Eric Legius, Maria Debiec-Rychter
Pages: 239 - 249Number of pages: 11 - Congenital enlargement of toes(2020)
Authors: Hilde Brems
Pages: 945 - 946Number of pages: 2 - Keratinocytic epidermal nevi associated with localized fibro-osseous lesions without hypophosphatemia(2020)
Authors: Lien Mestach, Satyamaanasa Polubothu, Alistair Calder, Ellen Denayer, Karolina Gholam, Eric Legius, Elena Levtchenko, An Van Laethem, Hilde Brems, Veronica A Kinsler, et al.
Pages: 890 - 895Number of pages: 6 - Genetic basis of neurofibromatosis type 1 and related conditions, including mosaicism(2020)
Authors: Eric Legius, Hilde Brems
Pages: 2285 - 2295Number of pages: 11