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Researcher
Ilaria Elia
- Disciplines:Molecular and cell biology
Affiliations
- Laboratory of Metabolic Regulation of Cell Function (Division)
Responsible
From1 Aug 2021 → Today - Laboratory of Metabolic Regulation of Cell Function (Division)
Member
From1 Aug 2021 → Today - Department of Cellular and Molecular Medicine (Department)
Member
From1 Oct 2020 → 31 Jul 2021 - Laboratory of Cellular Metabolism and Metabolic Regulation (VIB-KU Leuven) (Division)
Member
From1 Feb 2013 → 31 Dec 2018
Projects
1 - 10 of 11
- Exploring TCA and itaconate metabolism as drivers of CD8+ T cell exhaustion in local metastatic nichesFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Utilizing metabolism to modulate T cell differentiation in cancerFrom24 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating the metabolic requirements of CD8+ t cells in melanoma at a spatial levelFrom4 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Potentiating metabolic fitness of metastasis associated CD8+ T cells through spatial metabolomicsFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Unraveling the role of NAD+ metabolism in CD8+ T cells to modulate anti-tumor immunityFrom1 Oct 2022 → TodayFunding: BOF - projects
- Targeting metabolism to modulate T cell effector function in metastatic melanomaFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting metabolism to modulate T cell effector function in metastatic melanomaFrom1 Oct 2021 → 30 Sep 2023Funding: BOF - projects
- Unraveling metabolic targets for potentiating CD8+ T cell functionFrom22 Sep 2021 → 31 Mar 2023Funding: BOF - doctoral mandates
- PhD project: Unraveling metabolic targets for potentiating CD8+ T cell functionFrom24 Aug 2021 → TodayFunding: BOF - doctoral mandates
- Targeting metabolism to modulate T cell effector function in metastatic melanomaFrom1 Aug 2021 → TodayFunding: BOF - tenure track
Publications
1 - 10 of 23
- Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade.(2023)
Authors: Ilaria Elia
- The metabolic cross-talk between cancer and T cells(2023)
Authors: Ilaria Elia
Pages: 597 - 609 - Oncometabolite D-2HG alters T cell metabolism to impair CD8(+) T cell function(2022)
Authors: Ilaria Elia
Pages: 1519 - + - Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells(2022)
Authors: Ilaria Elia
Pages: 1137 - + - Altered propionate metabolism contributes to tumour progression and aggressiveness(2022)
Authors: Ilaria Elia, dorien Broekaert, Sarah-Maria Fendt
Pages: 435 - 443 - Integrating metabolic engineering and immunotherapy(2021)
Authors: Ilaria Elia
- Cell-specific transcriptional control of mitochondrial metabolism by TIF1 gamma drives erythropoiesis(2021)
Authors: Ilaria Elia
Pages: 716 - + - Age-induced accumulation of methylmalonic acid promotes tumour progression(2020)
Authors: dorien Broekaert, Ilaria Elia, Sarah-Maria Fendt
Pages: 283 - + - Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines(2020)
Authors: Ruben Boon, Manoj Kumar Gautam, Tine Tricot, Ilaria Elia, Jonathan De Smedt, Guy Eelen, Matthew Bird, Philip Roelandt, Ginevra Doglioni, Matteo Rossi, et al.
- Breast cancer cells rely on environmental pyruvate to shape the metastatic niche(2019)
Authors: Ilaria Elia, Matteo Rossi, Steve Stegen, dorien Broekaert, Ginevra Doglioni, Ruben Boon, Catherine Verfaillie, Erik Verbeken, Geert Carmeliet, Sarah-Maria Fendt
Pages: 117 - +