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Researcher
Ilse DEWACHTER
- Keywords:Biomedical sciences (incl. biochemistry)
- Disciplines:Inflammation, Innate immunity, Immunology not elsewhere classified, Cognitive neuroscience, Neuroanatomy, Neurological and neuromuscular diseases, Neurosciences not elsewhere classified, Protein diagnostics, Cell death, Cell signalling, Cellular interactions and extracellular matrix, Cytoskeleton
Affiliations
- Neurosciences (Department)
Member
From1 Jan 2020 → Today - Neurosciences (Research group)
Member
From1 Jan 2020 → Today - Neurosciences (Research group)
Responsible
From1 Jan 2020 → Today - Biomedical Research Institute (Research institute)
Member
From1 Jan 2017 → Today - Faculty of Medicine and Life Sciences (Faculty)
Member
From1 Jan 2017 → Today - Physiology - Biochemistry - Immunology (Department)
Member
From1 Jan 2017 → 31 Dec 2019 - Physiology (Research group)
Member
From1 Jan 2017 → 31 Dec 2019
Projects
1 - 10 of 18
- Identification of ApoE-dependent lipid pathways in microglia and their regulation by long non-coding RNAs (lncRNAs) for brain-specific targeting of neurodegeneration in Alzheimer’s DiseaseFrom1 Nov 2025 → TodayFunding: FWO fellowships
- MOTS-c in the Peloton of Exerkines: A Breakthrough for Vascular Health in Type 2 DiabetesFrom1 Nov 2025 → TodayFunding: BOF - doctoral mandates
- "Next-generation" therapies for Alzheimer's Disease by halting Tau Induced NeurodeGenerationFrom1 Jan 2025 → TodayFunding: Foundations, funds and other with scientific goal
- Lipid metabolism directed crosstalk between microglia and neurons as driver of neurodegeneration in MS and AD.From1 Jan 2025 → TodayFunding: BOF - iBOF
- Understanding the link between amyloid and tau pathology in Alzheimer's Disease, a focus on the role of ApoE and LDL receptor family.From1 Nov 2024 → TodayFunding: FWO fellowships
- The effect of exercise of high vs. moderate intensity on the brain intype 2 diabetesFrom1 Nov 2024 → TodayFunding: FWO fellowships
- Impact of volume versus intensity of exercise therapy on the brain in T2DM.From1 Jan 2023 → 31 Oct 2024Funding: BOF - doctoral mandates
- Halting amyloid induced tau pathology, by modifying ApoE-dependent lipid homeostasis: checking the FACTS on FATS as a modifiable target for preventing AD.From1 Jan 2023 → 31 Dec 2025Funding: Foundations, funds and other with scientific goal
- Personalized prevention and halting of Alzheimer's Disease progression along the ATN axis: Targeting ApoE, neuroinflammation and lipid metabolismFrom8 Jul 2022 → TodayFunding: BOF - Methusalem
- MULTISCALE - The UHasselt MultiScale Optical Imaging Core: Infrastructure for nano- to centimeter length scale microscopy and analysis of 'big' 4D datasetsFrom1 May 2022 → TodayFunding: Industrial enterprises, FWO Large scale research infrastructure, Foreign public sponsor, Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 38
- Gastrointestinal Dysfunction and Low-Grade Inflammation Associate With Enteric Neuronal Amyloid-β in a Model for Amyloid Pathology(2025)Published in: Neurogastroenterology and motilityISSN: 1350-1925
- Cytoskeletal control in adult microglia is essential to restore neurodevelopmental synaptic and cognitive deficits(2025)Published in: Science advancesISSN: 2375-2548Issue: 35Volume: 11
- Cytoskeletal control in adult microglia is essential to restore neurodevelopmental synaptic and cognitive deficits(2025)Published in: GliaISSN: 0894-1491Volume: 73Pages: E1248
- The Impact of Exercise Training on the Brain and Cognition in Type 2 Diabetes, and its Physiological Mediators: A Systematic Review(2025)Published in: Sports medicine - OpenISSN: 2199-1170Issue: 1Volume: 11
- A peek into the pipeline: Expert views on emerging therapies(2025)Published in: Cell Reports MedicineISSN: 2666-3791Issue: 4Volume: 6
- APOE deficiency inhibits amyloid-facilitated (A) tau pathology (T) and neurodegeneration (N), halting progressive ATN pathology in a preclinical model(2025)Published in: Molecular psychiatryISSN: 1359-4184
- The evolving landscape of Alzheimer's disease therapy: From AD to tau(2025)Published in: CellISSN: 0092-8674Issue: 26Volume: 188Pages: 7337 - 7354
- Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models(2024)Published in: Acta neuropathologica communicationsISSN: 2051-5960Issue: 1Volume: 12
- The role of APOE-mediated microglial response in Aβ and Tau pathologies(2024)Number of pages: 222
- Genomic stress and impaired DNA repair in Alzheimer disease(2024)Published in: DNA repairISSN: 1568-7864Volume: 139